Detailed information NTG0098774

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R8624_RS09430
• Genome accession: NZ_AP026930
• Coordinates: 1824765..1825226 (-)
• Length: 153 a.a.
• NCBI ID: WP_050120523.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701208
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1819765..1830226

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8624_RS09395 (PC1195_18260)	-	1820070..1820894 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
R8624_RS09400 (PC1195_18270)	rnpA	1820869..1821240 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R8624_RS09405	-	1821257..1821388 (-)	132	WP_000768904.1	hypothetical protein	-
R8624_RS09410 (PC1195_18280)	-	1821389..1822579 (-)	1191	WP_000167766.1	acetate kinase	-
R8624_RS09415 (PC1195_18290)	comYH	1822630..1823583 (-)	954	WP_050311715.1	class I SAM-dependent methyltransferase	Machinery gene
R8624_RS09420	-	1823644..1824238 (-)	595	Protein_1832	class I SAM-dependent methyltransferase	-
R8624_RS09425 (PC1195_18320)	comGG/cglG	1824341..1824787 (-)	447	WP_050311716.1	competence type IV pilus minor pilin ComGG	Machinery gene
R8624_RS09430 (PC1195_18330)	comGF/cglF	1824765..1825226 (-)	462	WP_050120523.1	competence type IV pilus minor pilin ComGF	Machinery gene
R8624_RS09435 (PC1195_18340)	comGE/cglE	1825189..1825491 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R8624_RS09440 (PC1195_18350)	comGD/cglD	1825454..1825858 (-)	405	WP_050311717.1	competence type IV pilus minor pilin ComGD	Machinery gene
R8624_RS09445 (PC1195_18360)	comGC/cglC	1825851..1826177 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
R8624_RS09450 (PC1195_18370)	comGB/cglB	1826179..1827195 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
R8624_RS09455 (PC1195_18380)	comGA/cglA/cilD	1827143..1828084 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
R8624_RS09460 (PC1195_18390)	-	1828160..1828525 (-)	366	WP_000286415.1	DUF1033 family protein	-
R8624_RS09465 (PC1195_18400)	-	1828676..1829734 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17835.35 Da
• Isoelectric Point: 6.4832

>NTDB_id=98774 R8624_RS09430 WP_050120523.1 1824765..1825226(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900701208]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGVLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=98774 R8624_RS09430 WP_050120523.1 1824765..1825226(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900701208]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGAGTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909