Detailed information NTG0098691

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R8615_RS09370
• Genome accession: NZ_AP026929
• Coordinates: 1827364..1828374 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900701114
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1822364..1833374

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8615_RS09345 (PC1101_18400)	-	1822429..1823643 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
R8615_RS09350 (PC1101_18410)	-	1823799..1824092 (-)	294	WP_000977366.1	hypothetical protein	-
R8615_RS09355 (PC1101_18420)	-	1824255..1824707 (+)	453	WP_000079148.1	universal stress protein	-
R8615_RS09360 (PC1101_18430)	-	1824742..1826130 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
R8615_RS09365 (PC1101_18440)	-	1826196..1827158 (+)	963	WP_001124777.1	asparaginase	-
R8615_RS09370 (PC1101_18450)	ccpA	1827364..1828374 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R8615_RS09375 (PC1101_18460)	-	1828799..1829398 (-)	600	WP_000866719.1	response regulator transcription factor	-
R8615_RS09380 (PC1101_18470)	-	1829400..1830497 (-)	1098	WP_000893546.1	sensor histidine kinase	-
R8615_RS09385 (PC1101_18480)	-	1830497..1831234 (-)	738	WP_000832834.1	ABC transporter permease	-
R8615_RS09390 (PC1101_18490)	-	1831236..1832120 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
R8615_RS09395 (PC1101_18500)	-	1832107..1832301 (-)	195	WP_000820180.1	hypothetical protein	-
R8615_RS09400 (PC1101_18510)	-	1832298..1832504 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=98691 R8615_RS09370 WP_000990607.1 1827364..1828374(-) (ccpA) [Streptococcus pneumoniae strain PZ900701114]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=98691 R8615_RS09370 WP_000990607.1 1827364..1828374(-) (ccpA) [Streptococcus pneumoniae strain PZ900701114]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568