Detailed information NTG0098613

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R8623_RS09425
• Genome accession: NZ_AP026928
• Coordinates: 1828735..1829745 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900700406
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1823735..1834745

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8623_RS09400 (PC0401_18250)	-	1823800..1825014 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
R8623_RS09405 (PC0401_18260)	-	1825170..1825463 (-)	294	WP_000977366.1	hypothetical protein	-
R8623_RS09410 (PC0401_18270)	-	1825626..1826078 (+)	453	WP_000079148.1	universal stress protein	-
R8623_RS09415 (PC0401_18280)	-	1826113..1827501 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
R8623_RS09420 (PC0401_18290)	-	1827567..1828529 (+)	963	WP_001124777.1	asparaginase	-
R8623_RS09425 (PC0401_18300)	ccpA	1828735..1829745 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R8623_RS09430 (PC0401_18310)	-	1830170..1830769 (-)	600	WP_000866719.1	response regulator transcription factor	-
R8623_RS09435 (PC0401_18320)	-	1830771..1831868 (-)	1098	WP_000893546.1	sensor histidine kinase	-
R8623_RS09440 (PC0401_18330)	-	1831868..1832605 (-)	738	WP_000832834.1	ABC transporter permease	-
R8623_RS09445 (PC0401_18340)	-	1832607..1833491 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
R8623_RS09450 (PC0401_18350)	-	1833478..1833672 (-)	195	WP_000820180.1	hypothetical protein	-
R8623_RS09455 (PC0401_18360)	-	1833669..1833875 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=98613 R8623_RS09425 WP_000990607.1 1828735..1829745(-) (ccpA) [Streptococcus pneumoniae strain PZ900700406]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=98613 R8623_RS09425 WP_000990607.1 1828735..1829745(-) (ccpA) [Streptococcus pneumoniae strain PZ900700406]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568