Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R8623_RS09200 Genome accession   NZ_AP026928
Coordinates   1783470..1784090 (-) Length   206 a.a.
NCBI ID   WP_000839909.1    Uniprot ID   A0A098Z2X2
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1778470..1789090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS09175 (PC0401_17810) recA 1778847..1780013 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R8623_RS09180 (PC0401_17820) cinA 1780068..1781324 (-) 1257 WP_000642704.1 competence/damage-inducible protein A Machinery gene
  R8623_RS09185 (PC0401_17830) brpA 1781409..1782425 (-) 1017 WP_054384455.1 biofilm formation/cell division transcriptional regulator BrpA -
  R8623_RS09190 (PC0401_17840) - 1782433..1782951 (-) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  R8623_RS09195 (PC0401_17850) tsaE 1782941..1783384 (-) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R8623_RS09200 (PC0401_17860) comM 1783470..1784090 (-) 621 WP_000839909.1 hypothetical protein Regulator
  R8623_RS09205 (PC0401_17870) - 1784473..1785336 (-) 864 WP_001093627.1 helix-turn-helix domain-containing protein -
  R8623_RS09210 (PC0401_17880) - 1785524..1785693 (+) 170 Protein_1801 PhrA family quorum-sensing system peptide -
  R8623_RS09215 (PC0401_17890) - 1786141..1787412 (+) 1272 WP_317649593.1 serine protease -
  R8623_RS09220 (PC0401_17900) cbpJ 1787431..1788426 (+) 996 WP_317649595.1 choline-binding protein CbpJ -
  R8623_RS09225 (PC0401_17910) ndk 1788650..1789063 (-) 414 WP_000438289.1 nucleoside-diphosphate kinase -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23540.66 Da        Isoelectric Point: 10.1254

>NTDB_id=98610 R8623_RS09200 WP_000839909.1 1783470..1784090(-) (comM) [Streptococcus pneumoniae strain PZ900700406]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=98610 R8623_RS09200 WP_000839909.1 1783470..1784090(-) (comM) [Streptococcus pneumoniae strain PZ900700406]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z2X2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.462

94.66

0.364
  comM Streptococcus mitis SK321

38.462

94.66

0.364

Multiple sequence alignment