Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R8623_RS02510 Genome accession   NZ_AP026928
Coordinates   491334..493010 (-) Length   558 a.a.
NCBI ID   WP_215729172.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 486334..498010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS02480 (PC0401_04830) - 486667..486996 (-) 330 WP_000132572.1 hypothetical protein -
  R8623_RS02485 (PC0401_04840) - 487272..487610 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  R8623_RS02490 (PC0401_04850) comE/blpR 487615..488352 (+) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  R8623_RS02495 (PC0401_04860) - 488366..489706 (+) 1341 WP_001017642.1 sensor histidine kinase -
  R8623_RS02500 (PC0401_04870) blpC 489777..489905 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  R8623_RS02505 (PC0401_04880) - 489962..491323 (-) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  R8623_RS02510 (PC0401_04890) comA/nlmT 491334..493010 (-) 1677 WP_215729172.1 peptide cleavage/export ABC transporter Regulator
  R8623_RS02515 (PC0401_04900) comA/nlmT 492904..493491 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8623_RS02520 (PC0401_04910) blpI 493780..493977 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  R8623_RS02525 (PC0401_04920) blpJ 494444..494713 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  R8623_RS02530 (PC0401_04930) blpK 494782..495030 (+) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  R8623_RS02535 (PC0401_04940) cipB 495274..495423 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  R8623_RS10930 - 495459..495524 (+) 66 Protein_499 ComC/BlpC family peptide pheromone/bacteriocin -
  R8623_RS02540 - 495527..495646 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R8623_RS02545 (PC0401_04960) - 496127..496485 (+) 359 Protein_501 immunity protein -
  R8623_RS02550 (PC0401_04980) - 497114..497497 (+) 384 WP_000877381.1 hypothetical protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62977.29 Da        Isoelectric Point: 6.7844

>NTDB_id=98570 R8623_RS02510 WP_215729172.1 491334..493010(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700406]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLVQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=98570 R8623_RS02510 WP_215729172.1 491334..493010(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700406]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGATTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGTACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGACATATTTCTATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.89

99.821

0.728
  comA Streptococcus mitis NCTC 12261

67.563

100

0.676
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus mitis SK321

67.025

100

0.67
  comA Streptococcus gordonii str. Challis substr. CH1

66.905

100

0.67
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668

Multiple sequence alignment