Detailed information NTG0098532

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R8611_RS09270
• Genome accession: NZ_AP026927
• Coordinates: 1818428..1819438 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900700178
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1813428..1824438

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8611_RS09250	-	1814729..1815021 (-)	293	Protein_1817	hypothetical protein	-
R8611_RS09255 (PC0174_18160)	-	1815183..1815635 (+)	453	WP_000079148.1	universal stress protein	-
R8611_RS09260 (PC0174_18170)	-	1815670..1817058 (-)	1389	WP_000453140.1	Cof-type HAD-IIB family hydrolase	-
R8611_RS09265 (PC0174_18180)	-	1817124..1818086 (+)	963	WP_001124782.1	asparaginase	-
R8611_RS09270 (PC0174_18190)	ccpA	1818428..1819438 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R8611_RS09275 (PC0174_18200)	-	1819863..1820462 (-)	600	WP_050199550.1	response regulator transcription factor	-
R8611_RS09280 (PC0174_18210)	-	1820464..1821561 (-)	1098	WP_050199545.1	sensor histidine kinase	-
R8611_RS09285 (PC0174_18220)	-	1821561..1822298 (-)	738	WP_023396473.1	ABC transporter permease	-
R8611_RS09290 (PC0174_18230)	-	1822300..1823184 (-)	885	WP_050199542.1	ABC transporter ATP-binding protein	-
R8611_RS09295 (PC0174_18240)	-	1823171..1823365 (-)	195	WP_000708872.1	hypothetical protein	-
R8611_RS09300 (PC0174_18250)	-	1823362..1823568 (-)	207	WP_050199538.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=98532 R8611_RS09270 WP_000990607.1 1818428..1819438(-) (ccpA) [Streptococcus pneumoniae strain PZ900700178]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=98532 R8611_RS09270 WP_000990607.1 1818428..1819438(-) (ccpA) [Streptococcus pneumoniae strain PZ900700178]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568