Detailed information    

insolico Bioinformatically predicted

Overview


Name   cipB   Type   Regulator
Locus tag   R8611_RS02460 Genome accession   NZ_AP026927
Coordinates   485446..485595 (+) Length   49 a.a.
NCBI ID   WP_001809846.1    Uniprot ID   Q00MV6
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   indirect induction of ComX; activation of comRS system (predicted from homology)   
Competence regulation

Genomic Context


Location: 480446..490595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS02430 (PC0174_04770) blpC 480670..480825 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  R8611_RS02435 (PC0174_04780) - 480882..482243 (-) 1362 WP_033705510.1 bacteriocin secretion accessory protein -
  R8611_RS02440 (PC0174_04790) comA/nlmT 482254..483930 (-) 1677 WP_307774337.1 peptide cleavage/export ABC transporter Regulator
  R8611_RS02445 (PC0174_04800) comA/nlmT 483824..484411 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8611_RS02450 (PC0174_04810) blpM 484729..484983 (+) 255 WP_033705509.1 two-peptide bacteriocin subunit BlpM -
  R8611_RS02455 (PC0174_04820) blpN 484999..485202 (+) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  R8611_RS02460 (PC0174_04830) cipB 485446..485595 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  R8611_RS10745 - 485631..485696 (+) 66 Protein_486 ComC/BlpC family peptide pheromone/bacteriocin -
  R8611_RS02465 - 485699..485818 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R8611_RS02470 (PC0174_04850) - 486286..486657 (+) 372 WP_033705507.1 hypothetical protein -
  R8611_RS02475 - 486818..487787 (+) 970 Protein_489 thioredoxin domain-containing protein -
  R8611_RS02480 (PC0174_04880) - 488034..488267 (+) 234 WP_033705506.1 bacteriocin class II family protein -
  R8611_RS02485 (PC0174_04890) - 488299..488988 (+) 690 WP_050199695.1 CPBP family intramembrane glutamic endopeptidase -
  R8611_RS02490 (PC0174_04900) blpZ 489030..489278 (+) 249 WP_000276506.1 immunity protein BlpZ -
  R8611_RS02495 - 489308..489919 (+) 612 WP_000394042.1 CPBP family intramembrane glutamic endopeptidase -

Sequence


Protein


Download         Length: 49 a.a.        Molecular weight: 5149.92 Da        Isoelectric Point: 4.0439

>NTDB_id=98494 R8611_RS02460 WP_001809846.1 485446..485595(+) (cipB) [Streptococcus pneumoniae strain PZ900700178]
MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDGCATTV

Nucleotide


Download         Length: 150 bp        

>NTDB_id=98494 R8611_RS02460 WP_001809846.1 485446..485595(+) (cipB) [Streptococcus pneumoniae strain PZ900700178]
ATGAATACAAAAATGATGTCACAATTTTCTGTTATGGATAATGAAATGCTTGCTTGCGTTGAAGGTGGAGATATTGATTG
GGGAAGAAAAATTAGTTGTGCAGCAGGGGTTGCATATGGCGCAATTGATGGGTGTGCAACAACGGTTTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q00MV6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cipB Streptococcus mutans UA159

53.061

100

0.531


Multiple sequence alignment