Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R8611_RS02440 Genome accession   NZ_AP026927
Coordinates   482254..483930 (-) Length   558 a.a.
NCBI ID   WP_307774337.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 477254..488930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS02410 (PC0174_04730) - 477586..477915 (-) 330 WP_000132572.1 hypothetical protein -
  R8611_RS02415 (PC0174_04740) - 478192..478530 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  R8611_RS02420 (PC0174_04750) comE/blpR 478535..479272 (+) 738 WP_001219137.1 LytTR family DNA-binding domain-containing protein Regulator
  R8611_RS02425 (PC0174_04760) - 479286..480626 (+) 1341 WP_001099893.1 sensor histidine kinase -
  R8611_RS02430 (PC0174_04770) blpC 480670..480825 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  R8611_RS02435 (PC0174_04780) - 480882..482243 (-) 1362 WP_033705510.1 bacteriocin secretion accessory protein -
  R8611_RS02440 (PC0174_04790) comA/nlmT 482254..483930 (-) 1677 WP_307774337.1 peptide cleavage/export ABC transporter Regulator
  R8611_RS02445 (PC0174_04800) comA/nlmT 483824..484411 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8611_RS02450 (PC0174_04810) blpM 484729..484983 (+) 255 WP_033705509.1 two-peptide bacteriocin subunit BlpM -
  R8611_RS02455 (PC0174_04820) blpN 484999..485202 (+) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  R8611_RS02460 (PC0174_04830) cipB 485446..485595 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  R8611_RS10745 - 485631..485696 (+) 66 Protein_486 ComC/BlpC family peptide pheromone/bacteriocin -
  R8611_RS02465 - 485699..485818 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R8611_RS02470 (PC0174_04850) - 486286..486657 (+) 372 WP_033705507.1 hypothetical protein -
  R8611_RS02475 - 486818..487787 (+) 970 Protein_489 thioredoxin domain-containing protein -
  R8611_RS02480 (PC0174_04880) - 488034..488267 (+) 234 WP_033705506.1 bacteriocin class II family protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 63042.35 Da        Isoelectric Point: 6.9863

>NTDB_id=98492 R8611_RS02440 WP_307774337.1 482254..483930(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700178]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQEILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKAHELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=98492 R8611_RS02440 WP_307774337.1 482254..483930(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700178]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGAAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTAAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTCATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(10-279)

ABC transporter (ABC_tran)

(341-490)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.352

99.821

0.722
  comA Streptococcus mitis NCTC 12261

67.384

100

0.674
  comA Streptococcus pneumoniae D39

67.025

100

0.67
  comA Streptococcus pneumoniae R6

67.025

100

0.67
  comA Streptococcus pneumoniae Rx1

67.025

100

0.67
  comA Streptococcus mitis SK321

66.846

100

0.668
  comA Streptococcus gordonii str. Challis substr. CH1

66.726

100

0.668
  comA Streptococcus pneumoniae TIGR4

66.667

100

0.667

Multiple sequence alignment