Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   V3C22_RS08400 Genome accession   NZ_CP183775
Coordinates   1713075..1715906 (-) Length   943 a.a.
NCBI ID   WP_226708937.1    Uniprot ID   -
Organism   Streptococcus mutans strain Xc     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1708075..1720906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3C22_RS08370 (V3C22_08370) nusB 1709102..1709530 (-) 429 WP_002264997.1 transcription antitermination factor NusB -
  V3C22_RS08375 (V3C22_08375) - 1709523..1709912 (-) 390 WP_002262661.1 Asp23/Gls24 family envelope stress response protein -
  V3C22_RS08380 (V3C22_08380) efp 1709955..1710515 (-) 561 WP_002262662.1 elongation factor P -
  V3C22_RS08385 (V3C22_08385) - 1710655..1711359 (+) 705 WP_002264996.1 ion transporter -
  V3C22_RS08390 (V3C22_08390) - 1711407..1711859 (-) 453 WP_002264995.1 deoxycytidylate deaminase -
  V3C22_RS08395 (V3C22_08395) - 1712021..1713085 (-) 1065 WP_002262665.1 M24 family metallopeptidase -
  V3C22_RS08400 (V3C22_08400) uvrA 1713075..1715906 (-) 2832 WP_226708937.1 excinuclease ABC subunit UvrA Machinery gene
  V3C22_RS08405 (V3C22_08405) - 1715956..1716177 (+) 222 WP_002280751.1 hypothetical protein -
  V3C22_RS08410 (V3C22_08410) - 1716574..1717518 (+) 945 WP_002262667.1 magnesium transporter CorA family protein -
  V3C22_RS08415 (V3C22_08415) - 1717673..1718335 (+) 663 WP_002304961.1 DUF1129 domain-containing protein -
  V3C22_RS08420 (V3C22_08420) hdrR 1718474..1718830 (+) 357 WP_002268419.1 LytTR family transcriptional regulator HdrR Regulator
  V3C22_RS08425 (V3C22_08425) hdrM 1718827..1719513 (+) 687 WP_002265269.1 hdrR negative regulator HdrM Regulator
  V3C22_RS08430 (V3C22_08430) - 1719521..1720240 (-) 720 WP_014677769.1 TraX family protein -
  V3C22_RS08435 (V3C22_08435) rpsR 1720559..1720798 (-) 240 WP_000068664.1 30S ribosomal protein S18 -

Sequence

Protein


Download         Length: 943 a.a.        Molecular weight: 104049.50 Da        Isoelectric Point: 6.7146

>NTDB_id=983292 V3C22_RS08400 WP_226708937.1 1713075..1715906(-) (uvrA) [Streptococcus mutans strain Xc]
MQDKLIIRGARAHNLKNIDVEIPRDKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMDKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGIPYCKNGHGAITASSVEQIVDQVLTLPERTRMQILAPVVRRKK
GQHKAVFDRIQKDGYVRVRIDGDIMDVAEVPELSKNKMHNIEVVVDRLVQKDGIRGRLFDSIEAALHLGDGYVIIDTMDD
HELIFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVIPDENKTLREGALAPWNPISSNYYPQLL
EQAMNAFGVDMDKPWKDLSDEDKKLVLHGSGDTAFHFHYQNDFGGVRDIDIPFEGIISNISRRYHETNSDFTRNVMRSYM
NELPCATCHGYRLNDQALSVRVGGEEGLNIGQVSELSIADHLSLLTHLELSENEKTIATPIVKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLISSLKKMRDLGNTLIVVEHDEDTMMAADWLV
DVGPGAGALGGEIVASGTPKQVAKNKKSITGQYLSGKKKIPVPLDRRKGSGRFIEIKGAAENNLQNINVKFPLGKFIAVT
GVSGSGKSTLVNSILKKVIAQKLNRNSEKPGKYKSISGIEHIDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGTRYNSETLEVHYKDKNIAEILNMTVNDAAEFF
APIPKIARKIRTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGQVIATGTPEQVAEMTESYTGQYLKGRLNEK

Nucleotide


Download         Length: 2832 bp        

>NTDB_id=983292 V3C22_RS08400 WP_226708937.1 1713075..1715906(-) (uvrA) [Streptococcus mutans strain Xc]
ATGCAAGATAAATTAATTATTCGTGGAGCGCGTGCTCATAACTTAAAAAATATAGATGTGGAAATTCCGCGTGATAAGTT
GATTGTCATGACGGGCTTATCGGGTTCAGGAAAGTCCAGTCTGGCTTTTGATACCATTTACGCCGAAGGGCAACGCCGTT
ATGTTGAGAGTTTATCGGCTTATGCTAGACAGTTTTTAGGAAATATGGATAAGCCTGATGTTGATTCGATTGATGGTCTT
AGCCCTGCTATTTCCATTGACCAAAAGACAACCAGTAAAAATCCACGTTCTACTGTTGGTACAGTTACAGAGATTAATGA
TTATCTCCGATTATTATATGCACGCGTTGGTATTCCTTATTGTAAAAATGGTCATGGTGCTATCACGGCTTCTTCAGTAG
AGCAAATTGTTGATCAAGTTTTGACCTTGCCTGAGCGGACACGAATGCAGATTTTGGCACCTGTTGTTCGGCGGAAAAAA
GGTCAACATAAGGCAGTATTTGATCGCATTCAAAAAGATGGCTATGTTCGTGTGCGTATAGATGGCGACATTATGGATGT
AGCAGAAGTTCCTGAACTTTCAAAAAATAAAATGCACAACATTGAAGTGGTTGTTGATCGTCTCGTGCAAAAGGATGGTA
TTAGAGGACGGTTGTTTGATTCCATTGAAGCAGCTTTGCATTTGGGAGATGGTTATGTCATCATTGATACTATGGATGAT
CATGAATTGATTTTCTCAGAACACTATTCTTGTCCTGTTTGTGGTTTTACTGTTCCAGAATTGGAACCGCGTCTCTTTTC
TTTTAATGCACCCTTTGGTTCTTGTCCTACCTGTGATGGTTTAGGGATTAAATTAGAAGTCGATTTGGACTTGGTTATTC
CAGATGAGAATAAGACTTTGAGAGAGGGAGCGCTGGCTCCTTGGAATCCTATTTCTTCAAACTATTATCCGCAGCTATTA
GAGCAGGCTATGAATGCTTTTGGTGTAGATATGGATAAACCTTGGAAAGATTTATCAGATGAGGATAAAAAACTCGTCTT
ACATGGTTCAGGTGACACAGCATTTCATTTTCATTATCAAAATGATTTTGGCGGTGTCAGGGATATTGATATTCCTTTTG
AAGGCATTATTAGCAATATTAGCCGCCGTTATCATGAAACTAATAGTGATTTCACACGTAATGTCATGCGCAGCTATATG
AATGAGCTGCCTTGTGCAACCTGTCATGGTTATCGACTCAATGATCAAGCTCTTAGTGTACGGGTTGGCGGCGAAGAAGG
CCTAAATATTGGTCAGGTATCTGAGCTATCCATTGCGGATCACTTGAGTTTGCTGACTCATTTGGAACTGTCAGAAAATG
AAAAAACCATTGCAACACCCATTGTCAAGGAAATTAAGGATCGTCTGACTTTCCTTAATAATGTGGGTCTTAATTATTTG
ACTTTATCACGCTCAGCAGGAACGCTATCAGGAGGTGAAAGCCAACGCATTCGTCTAGCAACTCAGATTGGTTCTAATTT
AAGCGGTGTACTTTATATTTTGGATGAACCTTCCATTGGTTTACATCAAAGAGATAACGACCGCCTTATTTCCAGTCTTA
AGAAAATGCGAGATTTGGGGAATACTTTGATTGTTGTCGAACATGATGAAGATACCATGATGGCAGCTGATTGGCTGGTT
GATGTTGGACCGGGAGCAGGTGCTTTAGGTGGTGAAATTGTTGCCTCAGGCACCCCAAAGCAAGTTGCTAAAAATAAAAA
GTCTATTACTGGACAGTATTTATCTGGTAAGAAAAAAATTCCTGTACCTTTGGATCGTCGTAAAGGGAGTGGCCGTTTCA
TTGAAATCAAAGGAGCAGCAGAAAACAATCTGCAAAACATTAATGTCAAATTTCCTCTTGGAAAATTTATTGCCGTTACA
GGTGTTTCGGGTTCTGGTAAATCAACACTGGTTAATAGTATTTTAAAAAAAGTCATTGCTCAAAAACTCAATCGTAATTC
TGAAAAGCCAGGCAAATACAAGTCTATTTCAGGAATTGAACATATTGATCGTTTAATTGACATTGATCAAAGCCCAATTG
GCCGTACACCAAGATCCAATCCTGCCACCTATACAGGTGTCTTTGATGATATTCGTGACCTTTTTGCTCAAACCAATGAA
GCTAAAATTCGCGGTTATAAGAAGGGACGTTTTTCTTTCAATGTTAAAGGCGGACGCTGCGAAGCCTGCTCAGGTGATGG
CATTATCAAAATTGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAAGTCTGTCATGGAACGCGTTATAATAGTG
AGACTTTGGAAGTTCATTACAAGGACAAAAATATTGCAGAAATTCTTAATATGACAGTCAATGACGCAGCAGAATTTTTT
GCACCGATTCCTAAAATTGCTCGCAAGATCCGAACCATTAAGGATGTTGGTCTGGGTTATGTGACTCTTGGACAGCCAGC
GACCACTTTATCAGGTGGGGAAGCGCAGCGCATGAAGTTAGCTTCTGAACTGCATAAACGCTCAACGGGAAAGAGTTTTT
ATATTCTTGATGAGCCTACAACTGGTCTCCATACAGATGATATTGCTAGACTTCTTAAAGTCTTAGAGCGCTTTGTTGAT
GATGGCAATACTGTGCTTGTCATTGAGCATAATTTGGACGTTATTAAAACAGCTGACCATATTATTGATTTGGGACCGGA
AGGCGGTGTTGGTGGTGGTCAAGTCATAGCGACTGGGACACCAGAACAAGTAGCTGAGATGACGGAAAGCTATACAGGAC
AGTATTTGAAGGGAAGACTAAATGAAAAATAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(624-860)

UvrA interaction domain (UvrA_inter)

(132-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

84.305

100

0.843
  uvrA Streptococcus pneumoniae TIGR4

84.305

100

0.843
  uvrA Streptococcus pneumoniae D39

84.305

100

0.843

Multiple sequence alignment