Detailed information NTG0098199

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: R8625_RS08480
• Genome accession: NZ_AP026923
• Coordinates: 1663620..1664687 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain PZ900700054
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1658620..1669687

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8625_RS08455 (PC0054_16820)	treR	1658790..1659500 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
R8625_RS08460 (PC0054_16830)	-	1659533..1660336 (-)	804	WP_115254439.1	ABC transporter ATP-binding protein	-
R8625_RS08465 (PC0054_16840)	-	1660349..1661242 (-)	894	WP_130894676.1	ABC transporter permease	-
R8625_RS08470	-	1661254..1662063 (-)	810	Protein_1674	ABC transporter substrate-binding protein	-
R8625_RS08475 (PC0054_16870)	amiF	1662683..1663609 (-)	927	WP_317649126.1	ATP-binding cassette domain-containing protein	Regulator
R8625_RS08480 (PC0054_16880)	amiE	1663620..1664687 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
R8625_RS08485 (PC0054_16890)	amiD	1664696..1665622 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
R8625_RS08490 (PC0054_16900)	amiC	1665622..1667118 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
R8625_RS08495 (PC0054_16910)	amiA3	1667185..1669164 (-)	1980	WP_000742236.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=98199 R8625_RS08480 WP_000159554.1 1663620..1664687(-) (amiE) [Streptococcus pneumoniae strain PZ900700054]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=98199 R8625_RS08480 WP_000159554.1 1663620..1664687(-) (amiE) [Streptococcus pneumoniae strain PZ900700054]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAAATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541