Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   R8625_RS05560 Genome accession   NZ_AP026923
Coordinates   1098162..1099511 (-) Length   449 a.a.
NCBI ID   WP_050201324.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1093162..1104511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS05535 (PC0054_10960) - 1094693..1095679 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  R8625_RS05540 (PC0054_10970) - 1095942..1096715 (-) 774 WP_000731126.1 potassium channel family protein -
  R8625_RS05545 (PC0054_10980) - 1096762..1097016 (-) 255 WP_001812387.1 type II toxin-antitoxin system RelE/ParE family toxin -
  R8625_RS05550 (PC0054_10990) relB 1097018..1097260 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  R8625_RS05555 (PC0054_11000) vicX 1097351..1098160 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  R8625_RS05560 (PC0054_11010) micB 1098162..1099511 (-) 1350 WP_050201324.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R8625_RS05565 (PC0054_11020) micA 1099504..1100208 (-) 705 WP_000722076.1 response regulator YycF Regulator
  R8625_RS05570 (PC0054_11030) mutY 1100263..1101438 (-) 1176 WP_317649041.1 A/G-specific adenine glycosylase -
  R8625_RS05575 - 1101535..1101660 (+) 126 WP_001818232.1 hypothetical protein -
  R8625_RS05580 (PC0054_11040) - 1101766..1103436 (-) 1671 WP_000845279.1 formate--tetrahydrofolate ligase -
  R8625_RS05585 (PC0054_11050) coaB 1103666..1104355 (+) 690 WP_000699480.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51796.53 Da        Isoelectric Point: 4.9135

>NTDB_id=98184 R8625_RS05560 WP_050201324.1 1098162..1099511(-) (micB) [Streptococcus pneumoniae strain PZ900700054]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESDFILGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=98184 R8625_RS05560 WP_050201324.1 1098162..1099511(-) (micB) [Streptococcus pneumoniae strain PZ900700054]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACCAACCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGA
CTTTATTTTAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTAGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAAACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCACCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(98-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.332

100

0.993
  vicK Streptococcus mutans UA159

69.403

89.532

0.621

Multiple sequence alignment