Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   AAFX12_RS10095 Genome accession   NZ_CP151938
Coordinates   2200023..2202278 (-) Length   751 a.a.
NCBI ID   WP_064367970.1    Uniprot ID   -
Organism   Vibrio alginolyticus strain TBV025     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2180286..2204899 2200023..2202278 within 0


Gene organization within MGE regions


Location: 2180286..2204899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFX12_RS10020 (AAFX12_10050) - 2180286..2181056 (-) 771 WP_005378438.1 ABC transporter ATP-binding protein -
  AAFX12_RS10025 (AAFX12_10055) - 2181321..2182796 (-) 1476 WP_017820023.1 hypothetical protein -
  AAFX12_RS10030 (AAFX12_10060) - 2183250..2184797 (+) 1548 WP_005378441.1 DUF3360 family protein -
  AAFX12_RS10035 (AAFX12_10065) pflB 2185101..2187377 (+) 2277 WP_005378442.1 formate C-acetyltransferase -
  AAFX12_RS10040 (AAFX12_10070) - 2187531..2188508 (+) 978 WP_005378443.1 lipid A deacylase LpxR family protein -
  AAFX12_RS10045 (AAFX12_10075) pflA 2188720..2189460 (+) 741 WP_064367976.1 pyruvate formate lyase 1-activating protein -
  AAFX12_RS10050 (AAFX12_10080) - 2189615..2190280 (+) 666 WP_005378445.1 energy-coupling factor ABC transporter permease -
  AAFX12_RS10055 (AAFX12_10085) - 2190417..2190917 (+) 501 WP_064367974.1 YfbU family protein -
  AAFX12_RS10060 (AAFX12_10090) - 2191411..2193345 (+) 1935 WP_005378447.1 PrkA family serine protein kinase -
  AAFX12_RS10065 (AAFX12_10095) - 2193393..2194664 (+) 1272 WP_005378448.1 YeaH/YhbH family protein -
  AAFX12_RS10070 (AAFX12_10100) - 2194676..2196235 (+) 1560 WP_005378449.1 SpoVR family protein -
  AAFX12_RS10075 (AAFX12_10105) kdsB 2196315..2197070 (-) 756 WP_064367973.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  AAFX12_RS10080 (AAFX12_10110) - 2197070..2197249 (-) 180 WP_005378451.1 Trm112 family protein -
  AAFX12_RS10085 (AAFX12_10115) lpxK 2197230..2198237 (-) 1008 WP_017820019.1 tetraacyldisaccharide 4'-kinase -
  AAFX12_RS10090 (AAFX12_10120) msbA 2198243..2199991 (-) 1749 WP_017820018.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  AAFX12_RS10095 (AAFX12_10125) comEC 2200023..2202278 (-) 2256 WP_064367970.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  AAFX12_RS10100 (AAFX12_10130) - 2202287..2202796 (+) 510 WP_005387834.1 DUF2062 domain-containing protein -
  AAFX12_RS10105 (AAFX12_10135) lolE 2202945..2204189 (-) 1245 WP_138940029.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  AAFX12_RS10110 (AAFX12_10140) lolD 2204192..2204899 (-) 708 WP_025766931.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -

Sequence

Protein


Download         Length: 751 a.a.        Molecular weight: 84332.16 Da        Isoelectric Point: 7.8762

>NTDB_id=981367 AAFX12_RS10095 WP_064367970.1 2200023..2202278(-) (comEC) [Vibrio alginolyticus strain TBV025]
MTLSEKSWTLALFVASVISSAWWPTIPDWRWLLLGIITTGSIIKLRRGLISIGAIAGFMVVIVHGNVLESQRQALFQAGE
NITIIGKVDSPFTQISHGYEGIVAIEAVNSQTLLPFLKPKIRLITPFPLDVNSEFTTSISLKPITGLRNEAGFDAEKHAM
GKNIIARAVVNKDAKWIVRSNVSLRQSIIADVADDVSSLHHFSLISALVFADRSWLSEEDWQALRDSGLLHLVSISGLHI
GMAFTFGLVVGGTVRYLLPQYQLLPSLYGLIFAVAYAWLADFSLPTTRAVSVCVVYVLLKYTLVHWTSWRVLLLAVSLQL
LVQPFASYSMSFWLSYLSVCAVLFAINLIRHQRGGWKERLKALLLTQLMLSALIVPVSGHFFSGFSLSSIAYNLVFIPWF
GFIVVPLMFLALFSSLFLEVIAKPLWHSVDWSLQPLSTSIQYAIGSWQPISMEMTMLVMAIVVCLIFQRFMSQYAWYLLL
GIVISIKLASEYEPHWRIDVLDVGHGLAVVVEKDDKVLLYDTGKAWQSGSIAEQVVTPVLHQRGYESIDTLILSHFDNDH
AGGRFFIEDAFSPQRKLSSQFFIGYEPCTRGDQWKWQGLNMEVLWPPALVQRAYNPHSCVLRLTDPISNFSMLFTGDIEA
ISEWILLREPGKLQSDVVLVPHHGSKSSSNPRFIEAVSPSVAVASLAKNNRWGMPAESVVASYRKLGITWLDTGEGGQVS
FFIHRDNWRSETKRSDTFEPWYRQMLRKGVE

Nucleotide


Download         Length: 2256 bp        

>NTDB_id=981367 AAFX12_RS10095 WP_064367970.1 2200023..2202278(-) (comEC) [Vibrio alginolyticus strain TBV025]
ATGACTCTCTCAGAAAAAAGTTGGACCTTGGCGTTATTTGTAGCGAGCGTAATCTCGTCGGCTTGGTGGCCGACAATACC
AGATTGGCGTTGGTTGCTGCTGGGAATAATAACCACTGGCTCAATAATCAAATTACGTCGTGGCTTAATTAGCATAGGCG
CAATTGCGGGCTTTATGGTTGTCATCGTCCACGGCAATGTATTGGAGTCTCAGAGACAAGCCCTTTTTCAAGCAGGGGAG
AATATTACCATAATTGGTAAAGTTGACAGCCCTTTTACGCAAATAAGTCACGGTTATGAAGGTATTGTCGCGATAGAAGC
GGTAAATTCTCAAACTCTGTTACCTTTTCTTAAACCTAAAATCCGTCTTATTACGCCTTTTCCACTCGATGTTAACAGTG
AGTTTACGACATCCATCTCGTTAAAGCCGATTACAGGTCTACGCAACGAAGCTGGCTTTGATGCTGAAAAGCACGCGATG
GGTAAAAATATTATCGCCCGAGCGGTTGTTAACAAAGACGCTAAGTGGATTGTTCGTTCTAATGTATCTCTGCGTCAATC
CATTATTGCCGATGTCGCTGATGATGTGTCTTCCCTTCATCATTTCTCGTTAATAAGTGCGTTAGTTTTTGCTGACCGTT
CTTGGTTGTCTGAGGAAGATTGGCAAGCGCTCAGGGACAGTGGTTTACTGCATTTGGTCTCCATTTCTGGTTTACATATT
GGTATGGCGTTTACTTTTGGGCTAGTCGTGGGCGGTACCGTTCGTTATCTATTACCCCAATACCAGTTGTTACCTAGCTT
ATATGGGCTGATCTTCGCTGTTGCCTACGCTTGGTTAGCGGATTTCTCTCTGCCTACTACGCGAGCAGTGTCGGTATGCG
TTGTTTACGTTCTCCTGAAGTATACTCTGGTGCACTGGACTTCTTGGCGAGTTCTTTTGCTTGCAGTATCTCTACAACTG
CTTGTCCAACCTTTTGCATCCTACAGTATGAGCTTTTGGTTATCGTACCTCTCCGTTTGTGCGGTATTGTTCGCAATTAA
TTTGATTCGACATCAAAGGGGAGGTTGGAAAGAGCGATTAAAAGCGTTATTGCTTACTCAATTGATGTTGAGCGCTTTAA
TCGTACCTGTTAGTGGCCATTTCTTCTCCGGTTTTAGTTTGTCCTCAATAGCCTACAACTTGGTATTTATTCCTTGGTTC
GGATTTATCGTTGTACCTTTGATGTTTCTAGCCCTGTTCTCATCTTTGTTTCTTGAAGTGATAGCGAAGCCTCTGTGGCA
TTCGGTGGACTGGTCATTACAGCCATTGAGCACGTCAATACAGTACGCAATAGGTTCTTGGCAACCTATTAGCATGGAAA
TGACAATGCTGGTTATGGCGATAGTGGTTTGCTTAATATTTCAACGGTTCATGTCTCAGTACGCGTGGTATTTGTTACTC
GGCATCGTTATTAGTATCAAGCTTGCATCGGAGTATGAACCGCATTGGCGTATCGATGTATTAGATGTAGGTCATGGCCT
TGCAGTGGTTGTAGAAAAAGACGACAAGGTGTTGCTGTATGACACTGGTAAAGCATGGCAAAGCGGCAGTATCGCAGAGC
AGGTCGTCACTCCGGTTTTGCATCAACGAGGTTATGAAAGCATAGATACACTGATTCTAAGCCATTTCGATAATGATCAC
GCAGGCGGCCGCTTTTTCATTGAAGATGCCTTTTCTCCACAGCGTAAACTTAGTAGTCAATTCTTTATCGGATATGAGCC
TTGCACTAGAGGTGACCAATGGAAATGGCAAGGATTAAACATGGAAGTGCTCTGGCCTCCTGCACTTGTTCAACGTGCGT
ATAATCCGCACTCCTGTGTATTACGACTTACTGACCCTATTTCTAACTTTAGTATGCTTTTTACTGGTGATATTGAGGCC
ATTAGCGAGTGGATTTTGCTTAGAGAACCCGGAAAGTTACAAAGCGATGTGGTGCTAGTCCCTCACCACGGGAGTAAAAG
TTCATCGAATCCTCGATTTATCGAGGCGGTGAGCCCGAGTGTGGCGGTTGCTTCTTTAGCAAAAAACAATCGATGGGGAA
TGCCAGCGGAAAGTGTCGTTGCTTCATACCGAAAGCTTGGCATTACTTGGCTTGATACTGGTGAGGGTGGTCAGGTAAGC
TTCTTTATTCACCGTGATAATTGGCGCTCAGAAACCAAACGTAGCGATACATTTGAGCCTTGGTATAGGCAGATGCTGCG
TAAGGGAGTAGAATGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(208-465)

Metallo-beta-lactamase superfamily (Lactamase_B)

(503-684)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio parahaemolyticus RIMD 2210633

68.883

100

0.69
  comEC Vibrio campbellii strain DS40M4

65.426

100

0.655
  comEC Vibrio cholerae strain A1552

43.634

100

0.438

Multiple sequence alignment