Detailed information NTG0098123

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: R8586_RS09385
• Genome accession: NZ_AP026922
• Coordinates: 1804715..1805782 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain PZ900700038
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1799715..1810782

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8586_RS09365	-	1800216..1801093 (-)	878	Protein_1852	ABC transporter permease	-
R8586_RS09370	-	1801138..1801914 (-)	777	Protein_1853	ABC transporter substrate-binding protein	-
R8586_RS09375 (PC0038_18750)	-	1802468..1803421 (-)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
R8586_RS09380 (PC0038_18760)	amiF	1803778..1804704 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
R8586_RS09385 (PC0038_18770)	amiE	1804715..1805782 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
R8586_RS09390 (PC0038_18780)	amiD	1805791..1806717 (-)	927	WP_000103697.1	oligopeptide ABC transporter permease OppC	Regulator
R8586_RS09395 (PC0038_18790)	amiC	1806717..1808213 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
R8586_RS09400 (PC0038_18800)	amiA3	1808280..1810259 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=98123 R8586_RS09385 WP_000159554.1 1804715..1805782(-) (amiE) [Streptococcus pneumoniae strain PZ900700038]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=98123 R8586_RS09385 WP_000159554.1 1804715..1805782(-) (amiE) [Streptococcus pneumoniae strain PZ900700038]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTCGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGATTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATTCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541