Detailed information NTG0979784

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: AAE282_RS13855
• Genome accession: NZ_CP151685
• Coordinates: 2640114..2640731 (-)
• Length: 205 a.a.
• NCBI ID: WP_004398514.1
• Uniprot ID: A0AAE2SLR2
• Organism: Bacillus subtilis strain YB-187
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2635114..2645731

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAE282_RS13825 (AAE282_13825)	rpsT	2635416..2635682 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
AAE282_RS13830 (AAE282_13830)	holA	2635697..2636740 (-)	1044	WP_003229987.1	DNA polymerase III subunit delta	-
AAE282_RS13835 (AAE282_13835)	-	2636780..2636929 (-)	150	WP_003229985.1	hypothetical protein	-
AAE282_RS13840 (AAE282_13840)	yqzM	2636970..2637104 (+)	135	WP_003229983.1	YqzM family protein	-
AAE282_RS13845 (AAE282_13845)	comEC	2637144..2639474 (-)	2331	WP_009967776.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AAE282_RS13850 (AAE282_13850)	comEB	2639478..2640047 (-)	570	WP_003229978.1	ComE operon protein 2	-
AAE282_RS13855 (AAE282_13855)	comEA	2640114..2640731 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
AAE282_RS13860 (AAE282_13860)	comER	2640815..2641636 (+)	822	WP_004398597.1	late competence protein ComER	-
AAE282_RS13865 (AAE282_13865)	yqeM	2641702..2642445 (-)	744	WP_003229973.1	class I SAM-dependent methyltransferase	-
AAE282_RS13870 (AAE282_13870)	rsfS	2642442..2642798 (-)	357	WP_003229971.1	ribosome silencing factor	-
AAE282_RS13875 (AAE282_13875)	yqeK	2642816..2643376 (-)	561	WP_004399059.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
AAE282_RS13880 (AAE282_13880)	nadD	2643366..2643935 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
AAE282_RS13885 (AAE282_13885)	yhbY	2643947..2644237 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
AAE282_RS13890 (AAE282_13890)	aroE	2644231..2645073 (-)	843	WP_003229967.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 21769.45 Da
• Isoelectric Point: 4.7220

>NTDB_id=979784 AAE282_RS13855 WP_004398514.1 2640114..2640731(-) (comEA) [Bacillus subtilis strain YB-187]
MNWLNQHKKAIILAASAAVFTAIMIFLATGKNKEPVKQAVPTETENTVVKQEANNDESNETIVIDIKGAVQHPGVYEMRT
GDRVSQAIEKAGGTSEQADEAQVNLAEILQDGTVVYIPKKGEETAVQQGGGGSVQSDGGKGALVNINTATLEELQGISGV
GPSKAEAIIAYREENGRFQTIEDITKVSGIGEKSFEKIKSSITVK

Nucleotide

• Length: 618 bp

>NTDB_id=979784 AAE282_RS13855 WP_004398514.1 2640114..2640731(-) (comEA) [Bacillus subtilis strain YB-187]
ATGAATTGGTTGAATCAGCATAAGAAAGCAATTATTTTAGCGGCTTCTGCGGCTGTTTTCACAGCGATTATGATCTTTCT
GGCCACAGGGAAAAATAAAGAGCCGGTGAAGCAAGCTGTACCAACAGAGACAGAAAATACAGTGGTAAAGCAGGAAGCAA
ACAACGACGAGTCAAACGAAACAATTGTGATAGACATCAAAGGTGCTGTTCAGCATCCTGGCGTTTATGAAATGCGAACA
GGGGACAGAGTATCTCAGGCAATTGAGAAAGCGGGCGGGACCAGTGAACAAGCAGACGAAGCGCAAGTAAATTTGGCGGA
GATTCTGCAGGACGGGACAGTGGTGTACATCCCGAAAAAGGGAGAGGAAACAGCAGTGCAGCAAGGTGGCGGAGGGTCTG
TCCAAAGCGATGGAGGGAAGGGAGCGCTGGTGAATATCAATACAGCAACCTTAGAGGAGTTACAAGGCATCTCAGGGGTG
GGGCCATCCAAAGCTGAAGCTATTATTGCATACCGGGAGGAAAACGGTCGTTTCCAAACAATTGAAGATATCACTAAGGT
TTCAGGAATAGGTGAAAAGTCATTTGAGAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (142-203)

• SLBB domain (SLBB) (63-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	100	100	1
comEA	Staphylococcus aureus MW2	37.273	100	0.4
comEA	Staphylococcus aureus N315	36.364	100	0.39