Detailed information NTG0979151

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: ACM67D_RS10285
• Genome accession: NZ_CP181245
• Coordinates: 1963969..1965195 (+)
• Length: 408 a.a.
• NCBI ID: WP_047920901.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain LNP 16626
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1958969..1970195

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM67D_RS10255 (ACM67D_10255)	-	1960002..1960130 (-)	129	WP_256204576.1	hypothetical protein	-
ACM67D_RS10260 (ACM67D_10260)	dksA	1960145..1960561 (-)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-
ACM67D_RS10265 (ACM67D_10265)	proC	1960709..1961500 (-)	792	WP_003690203.1	pyrroline-5-carboxylate reductase	-
ACM67D_RS10270 (ACM67D_10270)	-	1961549..1961956 (-)	408	WP_003690202.1	hypothetical protein	-
ACM67D_RS10275 (ACM67D_10275)	-	1961956..1962642 (-)	687	WP_003699139.1	YggS family pyridoxal phosphate-dependent enzyme	-
ACM67D_RS10280 (ACM67D_10280)	pilT	1962762..1963805 (+)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
ACM67D_RS10285 (ACM67D_10285)	pilU	1963969..1965195 (+)	1227	WP_047920901.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
ACM67D_RS10290 (ACM67D_10290)	yccS	1965312..1967462 (+)	2151	WP_003697785.1	YccS family putative transporter	-
ACM67D_RS10295 (ACM67D_10295)	-	1967945..1968229 (-)	285	WP_003701816.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45670.27 Da
• Isoelectric Point: 7.0921

>NTDB_id=979151 ACM67D_RS10285 WP_047920901.1 1963969..1965195(+) (pilU) [Neisseria gonorrhoeae strain LNP 16626]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGTHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYYSQGSAGLVLRRINHVIPQMQELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=979151 ACM67D_RS10285 WP_047920901.1 1963969..1965195(+) (pilU) [Neisseria gonorrhoeae strain LNP 16626]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCACACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACTACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCAGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAGGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	45.225	87.255	0.395
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387