Detailed information NTG0097901

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R8613_RS09905
• Genome accession: NZ_AP026919
• Coordinates: 1894856..1895866 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900700012
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1889856..1900866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8613_RS09880 (PC0012_19180)	-	1891055..1891360 (-)	306	WP_025173140.1	hypothetical protein	-
R8613_RS09885 (PC0012_19190)	-	1891522..1891974 (+)	453	WP_000079148.1	universal stress protein	-
R8613_RS09890 (PC0012_19200)	-	1892009..1893397 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
R8613_RS09895 (PC0012_19210)	-	1893463..1894425 (+)	963	WP_001124777.1	asparaginase	-
R8613_RS09900 (PC0012_19220)	-	1894454..1894792 (-)	339	WP_317648250.1	hypothetical protein	-
R8613_RS09905 (PC0012_19230)	ccpA	1894856..1895866 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R8613_RS09910 (PC0012_19240)	-	1896291..1896890 (-)	600	WP_033705598.1	response regulator transcription factor	-
R8613_RS09915 (PC0012_19250)	-	1896892..1897989 (-)	1098	WP_317648253.1	sensor histidine kinase	-
R8613_RS09920 (PC0012_19260)	-	1897989..1898726 (-)	738	WP_000832839.1	ABC transporter permease	-
R8613_RS09925 (PC0012_19270)	-	1898728..1899612 (-)	885	WP_317648255.1	ABC transporter ATP-binding protein	-
R8613_RS09930 (PC0012_19280)	-	1899599..1899793 (-)	195	WP_000820185.1	hypothetical protein	-
R8613_RS09935 (PC0012_19290)	-	1899790..1899996 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=97901 R8613_RS09905 WP_000990607.1 1894856..1895866(-) (ccpA) [Streptococcus pneumoniae strain PZ900700012]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=97901 R8613_RS09905 WP_000990607.1 1894856..1895866(-) (ccpA) [Streptococcus pneumoniae strain PZ900700012]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCCAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568