Detailed information NTG0978683

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: MGAS37835_RS02340
• Genome accession: NZ_CP151475
• Coordinates: 438820..439821 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS37835
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 433820..444821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37835_RS02315 (MGAS37835_00960)	-	434494..435177 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
MGAS37835_RS02320 (MGAS37835_00962)	-	435388..436314 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
MGAS37835_RS02325 (MGAS37835_00964)	-	436459..436836 (-)	378	WP_002985686.1	VOC family protein	-
MGAS37835_RS02330 (MGAS37835_00966)	-	436847..437512 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
MGAS37835_RS02335 (MGAS37835_00968)	-	437561..438646 (-)	1086	WP_002985682.1	Xaa-Pro peptidase family protein	-
MGAS37835_RS02340 (MGAS37835_00970)	ccpA	438820..439821 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
MGAS37835_RS02345 (MGAS37835_00972)	-	439952..440950 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
MGAS37835_RS02350 (MGAS37835_00974)	-	440952..442286 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
MGAS37835_RS02355 (MGAS37835_00976)	thrS	442708..444651 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=978683 MGAS37835_RS02340 WP_002985680.1 438820..439821(+) (ccpA) [Streptococcus pyogenes strain MGAS37835]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=978683 MGAS37835_RS02340 WP_002985680.1 438820..439821(+) (ccpA) [Streptococcus pyogenes strain MGAS37835]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559