Detailed information NTG0978009

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACM6EM_RS09085
• Genome accession: NZ_CP181134
• Coordinates: 1861546..1862535 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain AG21-0594
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1856546..1867535

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6EM_RS09070 (ACM6EM_09070)	acsA	1857747..1859453 (-)	1707	WP_000862083.1	acetate--CoA ligase	-
ACM6EM_RS09075 (ACM6EM_09075)	-	1859622..1860254 (+)	633	WP_001015996.1	hypothetical protein	-
ACM6EM_RS09080 (ACM6EM_09080)	-	1860279..1861448 (+)	1170	WP_001184005.1	acetoin utilization protein AcuC	-
ACM6EM_RS09085 (ACM6EM_09085)	ccpA	1861546..1862535 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
ACM6EM_RS09090 (ACM6EM_09090)	-	1862608..1862721 (-)	114	WP_001788994.1	hypothetical protein	-
ACM6EM_RS09095 (ACM6EM_09095)	-	1863075..1864166 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
ACM6EM_RS09100 (ACM6EM_09100)	-	1864627..1864731 (-)	105	WP_001791758.1	hypothetical protein	-
ACM6EM_RS09105 (ACM6EM_09105)	-	1864866..1866224 (-)	1359	WP_000193917.1	hypothetical protein	-
ACM6EM_RS09110 (ACM6EM_09110)	-	1866298..1866789 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=978009 ACM6EM_RS09085 WP_000219066.1 1861546..1862535(-) (ccpA) [Staphylococcus aureus strain AG21-0594]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=978009 ACM6EM_RS09085 WP_000219066.1 1861546..1862535(-) (ccpA) [Staphylococcus aureus strain AG21-0594]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462