Detailed information NTG0977917

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: MGAS37832_RS00705
• Genome accession: NZ_CP151458
• Coordinates: 106566..107000 (+)
• Length: 144 a.a.
• NCBI ID: WP_010921800.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS37832
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 101566..112000

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37832_RS00675 (MGAS37832_00274)	-	103235..103600 (+)	366	WP_002986560.1	DUF1033 family protein	-
MGAS37832_RS00680 (MGAS37832_00276)	comYA	103693..104631 (+)	939	WP_010921798.1	competence type IV pilus ATPase ComGA	Machinery gene
MGAS37832_RS00685 (MGAS37832_00278)	comYB	104567..105601 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGAS37832_RS00690 (MGAS37832_00280)	comYC	105603..105929 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
MGAS37832_RS00695 (MGAS37832_00282)	comGD	105904..106332 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
MGAS37832_RS00700 (MGAS37832_00284)	comGE	106289..106573 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
MGAS37832_RS00705 (MGAS37832_00286)	comYF	106566..107000 (+)	435	WP_010921800.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGAS37832_RS00710 (MGAS37832_00288)	comGG	106984..107310 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
MGAS37832_RS00715 (MGAS37832_00290)	comYH	107408..108361 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
MGAS37832_RS00720 (MGAS37832_00292)	-	108420..109616 (+)	1197	WP_010921803.1	acetate kinase	-
MGAS37832_RS00725	-	109803..110111 (+)	309	WP_010921804.1	hypothetical protein	-
MGAS37832_RS00730 (MGAS37832_00294)	proC	110194..110964 (-)	771	WP_010921805.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16654.28 Da
• Isoelectric Point: 10.2526

>NTDB_id=977917 MGAS37832_RS00705 WP_010921800.1 106566..107000(+) (comYF) [Streptococcus pyogenes strain MGAS37832]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=977917 MGAS37832_RS00705 WP_010921800.1 106566..107000(+) (comYF) [Streptococcus pyogenes strain MGAS37832]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGGTTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	47.445	95.139	0.451
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae D39	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae R6	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae TIGR4	42.857	92.361	0.396
comGF/cglF	Streptococcus mitis SK321	42.105	92.361	0.389