Detailed information NTG0977567

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACM6AF_RS09065
• Genome accession: NZ_CP181120
• Coordinates: 1858878..1859867 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain AG21-0606
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1853878..1864867

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AF_RS09050 (ACM6AF_09055)	acsA	1855079..1856785 (-)	1707	WP_000862083.1	acetate--CoA ligase	-
ACM6AF_RS09055 (ACM6AF_09060)	-	1856954..1857586 (+)	633	WP_001015996.1	hypothetical protein	-
ACM6AF_RS09060 (ACM6AF_09065)	-	1857611..1858780 (+)	1170	WP_001184005.1	acetoin utilization protein AcuC	-
ACM6AF_RS09065 (ACM6AF_09070)	ccpA	1858878..1859867 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
ACM6AF_RS09070 (ACM6AF_09075)	-	1859940..1860053 (-)	114	WP_001788994.1	hypothetical protein	-
ACM6AF_RS09075 (ACM6AF_09080)	-	1860407..1861498 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
ACM6AF_RS09080 (ACM6AF_09085)	-	1861959..1862063 (-)	105	WP_001791758.1	hypothetical protein	-
ACM6AF_RS09085 (ACM6AF_09090)	-	1862198..1863556 (-)	1359	WP_000193917.1	hypothetical protein	-
ACM6AF_RS09090 (ACM6AF_09095)	-	1863630..1864121 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=977567 ACM6AF_RS09065 WP_000219066.1 1858878..1859867(-) (ccpA) [Staphylococcus aureus strain AG21-0606]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=977567 ACM6AF_RS09065 WP_000219066.1 1858878..1859867(-) (ccpA) [Staphylococcus aureus strain AG21-0606]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462