Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   R8563_RS05860 Genome accession   NZ_AP026917
Coordinates   1146860..1147669 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain PZ900700007     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1141860..1152669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8563_RS05840 (PC0007_11430) - 1144194..1145180 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  R8563_RS05845 (PC0007_11440) - 1145481..1146224 (-) 744 Protein_1153 potassium channel family protein -
  R8563_RS05850 (PC0007_11450) - 1146271..1146525 (-) 255 WP_001823540.1 type II toxin-antitoxin system RelE/ParE family toxin -
  R8563_RS05855 (PC0007_11460) relB 1146527..1146769 (-) 243 WP_054383105.1 type II toxin-antitoxin system RelB family antitoxin -
  R8563_RS05860 (PC0007_11470) vicX 1146860..1147669 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  R8563_RS05865 (PC0007_11480) micB 1147671..1149020 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R8563_RS05870 (PC0007_11490) micA 1149013..1149717 (-) 705 WP_000722076.1 response regulator YycF Regulator
  R8563_RS05875 (PC0007_11500) mutY 1149772..1150947 (-) 1176 WP_000886145.1 A/G-specific adenine glycosylase -
  R8563_RS05880 - 1151044..1151169 (+) 126 WP_001818232.1 hypothetical protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=97716 R8563_RS05860 WP_001289493.1 1146860..1147669(-) (vicX) [Streptococcus pneumoniae strain PZ900700007]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=97716 R8563_RS05860 WP_001289493.1 1146860..1147669(-) (vicX) [Streptococcus pneumoniae strain PZ900700007]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAGACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAATAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment