Detailed information NTG0976806

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: MGAS38343_RS02365
• Genome accession: NZ_CP151438
• Coordinates: 439131..440132 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS38343
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 434131..445132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS38343_RS02340 (MGAS38343_00962)	-	434805..435488 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
MGAS38343_RS02345 (MGAS38343_00964)	-	435699..436625 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
MGAS38343_RS02350 (MGAS38343_00966)	-	436770..437147 (-)	378	WP_002985686.1	VOC family protein	-
MGAS38343_RS02355 (MGAS38343_00968)	-	437158..437823 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
MGAS38343_RS02360 (MGAS38343_00970)	-	437872..438957 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
MGAS38343_RS02365 (MGAS38343_00972)	ccpA	439131..440132 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
MGAS38343_RS02370 (MGAS38343_00974)	-	440263..441261 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
MGAS38343_RS02375 (MGAS38343_00976)	-	441263..442597 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
MGAS38343_RS02380 (MGAS38343_00978)	thrS	443019..444962 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=976806 MGAS38343_RS02365 WP_002985680.1 439131..440132(+) (ccpA) [Streptococcus pyogenes strain MGAS38343]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=976806 MGAS38343_RS02365 WP_002985680.1 439131..440132(+) (ccpA) [Streptococcus pyogenes strain MGAS38343]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559