Detailed information NTG0097668

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R8522_RS10130
• Genome accession: NZ_AP026916
• Coordinates: 1971075..1972085 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900700006
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1966075..1977085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8522_RS10105	-	1967331..1967624 (-)	294	WP_000977374.1	hypothetical protein	-
R8522_RS10110 (PC0006_20350)	-	1967786..1968238 (+)	453	WP_000079148.1	universal stress protein	-
R8522_RS10115 (PC0006_20360)	-	1968273..1969661 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
R8522_RS10120 (PC0006_20370)	-	1969727..1970689 (+)	963	WP_050123719.1	asparaginase	-
R8522_RS10125 (PC0006_20380)	-	1970718..1971011 (-)	294	WP_050123718.1	hypothetical protein	-
R8522_RS10130 (PC0006_20390)	ccpA	1971075..1972085 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R8522_RS10135 (PC0006_20400)	-	1972510..1973109 (-)	600	WP_000866730.1	response regulator transcription factor	-
R8522_RS10140 (PC0006_20410)	-	1973111..1974208 (-)	1098	WP_050123714.1	sensor histidine kinase	-
R8522_RS10145 (PC0006_20420)	-	1974208..1974945 (-)	738	WP_000832843.1	ABC transporter permease	-
R8522_RS10150 (PC0006_20430)	-	1974947..1975831 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
R8522_RS10155 (PC0006_20440)	-	1975818..1976012 (-)	195	WP_000820182.1	hypothetical protein	-
R8522_RS10160 (PC0006_20450)	-	1976009..1976215 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=97668 R8522_RS10130 WP_000990607.1 1971075..1972085(-) (ccpA) [Streptococcus pneumoniae strain PZ900700006]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=97668 R8522_RS10130 WP_000990607.1 1971075..1972085(-) (ccpA) [Streptococcus pneumoniae strain PZ900700006]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568