Detailed information    

insolico Bioinformatically predicted

Overview


Name   cipB   Type   Regulator
Locus tag   R8522_RS02580 Genome accession   NZ_AP026916
Coordinates   501713..501862 (+) Length   49 a.a.
NCBI ID   WP_001809846.1    Uniprot ID   Q00MV6
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   indirect induction of ComX; activation of comRS system (predicted from homology)   
Competence regulation

Genomic Context


Location: 496713..506862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS02555 (PC0006_05190) comA/nlmT 497745..499421 (-) 1677 WP_196302068.1 peptide cleavage/export ABC transporter Regulator
  R8522_RS02560 (PC0006_05200) comA/nlmT 499315..499902 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8522_RS02565 (PC0006_05210) blpI 500183..500380 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  R8522_RS02570 (PC0006_05230) blpJ 500847..501116 (+) 270 WP_050122544.1 bacteriocin-like peptide BlpJ -
  R8522_RS02575 (PC0006_05240) - 501185..501469 (+) 285 WP_050122547.1 Blp family class II bacteriocin -
  R8522_RS02580 (PC0006_05250) cipB 501713..501862 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  R8522_RS02585 - 501966..502085 (+) 120 WP_001833623.1 PncF family bacteriocin immunity protein -
  R8522_RS02590 (PC0006_05270) - 502567..502925 (+) 359 Protein_511 immunity protein -
  R8522_RS02595 - 503086..504055 (+) 970 Protein_512 thioredoxin domain-containing protein -
  R8522_RS02600 (PC0006_05300) - 504302..504535 (+) 234 WP_050122549.1 bacteriocin class II family protein -
  R8522_RS02605 (PC0006_05310) - 504567..505256 (+) 690 WP_000760541.1 CPBP family intramembrane glutamic endopeptidase -
  R8522_RS02610 (PC0006_05320) blpZ 505298..505546 (+) 249 WP_000276499.1 immunity protein BlpZ -
  R8522_RS02615 - 505576..506187 (+) 612 WP_050122551.1 CPBP family intramembrane glutamic endopeptidase -

Sequence


Protein


Download         Length: 49 a.a.        Molecular weight: 5149.92 Da        Isoelectric Point: 4.0439

>NTDB_id=97629 R8522_RS02580 WP_001809846.1 501713..501862(+) (cipB) [Streptococcus pneumoniae strain PZ900700006]
MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDGCATTV

Nucleotide


Download         Length: 150 bp        

>NTDB_id=97629 R8522_RS02580 WP_001809846.1 501713..501862(+) (cipB) [Streptococcus pneumoniae strain PZ900700006]
ATGAATACAAAAATGATGTCACAATTTTCTGTTATGGATAATGAAATGCTTGCTTGCGTTGAAGGTGGAGATATTGATTG
GGGAAGAAAAATTAGTTGTGCAGCAGGGGTTGCATATGGCGCAATTGATGGGTGTGCAACAACGGTTTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q00MV6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cipB Streptococcus mutans UA159

53.061

100

0.531


Multiple sequence alignment