Detailed information NTG0097580

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: R8775_RS08740
• Genome accession: NZ_AP026915
• Coordinates: 1688853..1689920 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain PZ900700005
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1683853..1694920

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8775_RS08715 (PC0005_17210)	treR	1684040..1684750 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
R8775_RS08720 (PC0005_17220)	-	1684783..1685586 (-)	804	WP_000157656.1	ABC transporter ATP-binding protein	-
R8775_RS08725	-	1685599..1686476 (-)	878	Protein_1729	ABC transporter permease	-
R8775_RS08730	-	1686488..1687297 (-)	810	Protein_1730	ABC transporter substrate-binding protein	-
R8775_RS08735 (PC0005_17270)	amiF	1687916..1688842 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
R8775_RS08740 (PC0005_17280)	amiE	1688853..1689920 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
R8775_RS08745 (PC0005_17290)	amiD	1689929..1690855 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
R8775_RS08750 (PC0005_17300)	amiC	1690855..1692351 (-)	1497	WP_000759907.1	ABC transporter permease	Regulator
R8775_RS08755 (PC0005_17310)	amiA3	1692418..1694397 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=97580 R8775_RS08740 WP_000159554.1 1688853..1689920(-) (amiE) [Streptococcus pneumoniae strain PZ900700005]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=97580 R8775_RS08740 WP_000159554.1 1688853..1689920(-) (amiE) [Streptococcus pneumoniae strain PZ900700005]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541