Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   AADP84_RS06155 Genome accession   NZ_CP151186
Coordinates   1247961..1248935 (+) Length   324 a.a.
NCBI ID   WP_031787262.1    Uniprot ID   A0A7U7JUV7
Organism   Staphylococcus argenteus strain Dubai-25     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1242961..1253935
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AADP84_RS06120 (AADP84_06120) rpmG 1243418..1243567 (+) 150 WP_001265709.1 50S ribosomal protein L33 -
  AADP84_RS06125 (AADP84_06125) - 1243779..1244318 (+) 540 WP_072324191.1 5-formyltetrahydrofolate cyclo-ligase -
  AADP84_RS06130 (AADP84_06130) - 1244330..1245793 (+) 1464 WP_031787264.1 rhomboid family intramembrane serine protease -
  AADP84_RS06135 (AADP84_06135) - 1245774..1245974 (+) 201 WP_000087563.1 YqgQ family protein -
  AADP84_RS06140 (AADP84_06140) - 1245974..1246960 (+) 987 WP_000161316.1 ROK family glucokinase -
  AADP84_RS06145 (AADP84_06145) - 1246960..1247289 (+) 330 WP_001018874.1 MTH1187 family thiamine-binding protein -
  AADP84_RS06150 (AADP84_06150) - 1247286..1247909 (+) 624 WP_031787263.1 MBL fold metallo-hydrolase -
  AADP84_RS06155 (AADP84_06155) comGA 1247961..1248935 (+) 975 WP_031787262.1 competence type IV pilus ATPase ComGA Machinery gene
  AADP84_RS06160 (AADP84_06160) comGB 1248907..1249977 (+) 1071 WP_031787261.1 competence type IV pilus assembly protein ComGB Machinery gene
  AADP84_RS06165 (AADP84_06165) comGC 1249992..1250303 (+) 312 WP_000921699.1 competence type IV pilus major pilin ComGC Machinery gene
  AADP84_RS06170 (AADP84_06170) comGD 1250281..1250727 (+) 447 WP_072324131.1 competence type IV pilus minor pilin ComGD Machinery gene
  AADP84_RS06175 (AADP84_06175) comGE 1250714..1251013 (+) 300 WP_031787259.1 hypothetical protein Machinery gene
  AADP84_RS06180 (AADP84_06180) comGF 1250973..1251428 (+) 456 WP_078097699.1 competence type IV pilus minor pilin ComGF Machinery gene
  AADP84_RS06185 (AADP84_06185) - 1251527..1251676 (+) 150 WP_072324192.1 hypothetical protein -
  AADP84_RS06190 (AADP84_06190) - 1251663..1252187 (+) 525 WP_031787256.1 shikimate kinase -
  AADP84_RS06195 (AADP84_06195) gcvT 1252344..1253435 (+) 1092 WP_000093342.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36867.03 Da        Isoelectric Point: 9.0234

>NTDB_id=975753 AADP84_RS06155 WP_031787262.1 1247961..1248935(+) (comGA) [Staphylococcus argenteus strain Dubai-25]
MKILFQEIINKAIVMKASDVHFIPVHNEVSIKFRINDNLEQYEEIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQYFKQTKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNEKAGINYVNSFKAILRCDPDVILIGEIRDKEVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLQYFFSHNHSLPTSFKKLETKLDDMTKAGVICESTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=975753 AADP84_RS06155 WP_031787262.1 1247961..1248935(+) (comGA) [Staphylococcus argenteus strain Dubai-25]
ATGAAGATATTATTTCAAGAGATAATCAACAAAGCGATAGTAATGAAAGCGAGTGATGTCCATTTTATTCCTGTTCATAA
TGAAGTGAGTATTAAATTTCGTATAAATGACAATTTGGAACAGTATGAAGAAATTGGAAATAGTATTTATCAAAAGCTAT
TAGTTTATATGAAATTTCAAGCTGGTCTCGATGTATCTACGCAACAAGTTGCTCAGAGTGGTCGTTATAGCTACCATTTT
AATAAAATTTATTTTTTAAGAATTTCAACATTGCCATTATCACTTGGTCAAGAAAGTTGTGTGATAAGAATAGTTCCTCA
ATATTTTAAACAAACTAAATCAACATATAAATTTAATGATTTTAAACATTTAATGAATAAGAAACAAGGCTTATTGTTAT
TTAGTGGTCCGACGGGTTCAGGTAAAAGTACTTTAATGTATCAAATGGTCTCATACGCTAACAAAGCGTTAAACTTAAAT
GTTATATCTATTGAAGACCCAGTAGAAATGCAAATTCCTGGAATAGTTCAAATAAACGTAAATGAAAAAGCTGGGATTAA
CTATGTCAATTCATTTAAAGCGATATTAAGGTGTGACCCAGATGTTATTCTTATAGGGGAAATTAGAGATAAAGAAGTAG
CTAAATGTGTCATCCAAGCAAGTTTAAGTGGTCATCTAGTACTCACTACCTTACATGCAACAGATTGTAAAGGTGCAATT
TTAAGATTACTAGAAATGGGGATTTCAGTACAAGAACTAATACAAGCAACTAATTTAATTATAAATCAAAGACTTGTTAC
TACAATTAAACAGCAACGACAATTAGTGTGTGAAATTTTATCACAACAACAACTTCAGTATTTCTTCTCGCATAATCATT
CATTACCTACCTCATTTAAAAAACTAGAAACAAAGCTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAAGTACAATG
GATAAGTATATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7JUV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

95.988

100

0.96
  comGA Staphylococcus aureus N315

95.988

100

0.96

Multiple sequence alignment