Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   UXQ48_RS09560 Genome accession   NZ_CP151138
Coordinates   1952687..1953316 (-) Length   209 a.a.
NCBI ID   WP_341532650.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BSN164     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1947687..1958316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UXQ48_RS09530 (UXQ48_09530) - 1948107..1948637 (-) 531 WP_000184383.1 acyl-CoA thioesterase -
  UXQ48_RS09535 (UXQ48_09535) - 1948727..1949983 (-) 1257 WP_001795108.1 aminopeptidase -
  UXQ48_RS09540 (UXQ48_09540) - 1949986..1950186 (-) 201 WP_000180460.1 DUF1128 family protein -
  UXQ48_RS09545 (UXQ48_09545) - 1950333..1950797 (+) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  UXQ48_RS09550 (UXQ48_09550) - 1950804..1951079 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  UXQ48_RS09555 (UXQ48_09555) - 1951357..1952574 (+) 1218 WP_000037075.1 YihY/virulence factor BrkB family protein -
  UXQ48_RS09560 (UXQ48_09560) vraR 1952687..1953316 (-) 630 WP_341532650.1 two-component system response regulator VraR Regulator
  UXQ48_RS09565 (UXQ48_09565) vraS 1953306..1954349 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  UXQ48_RS09570 (UXQ48_09570) liaF 1954346..1955047 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  UXQ48_RS09575 (UXQ48_09575) - 1955062..1955448 (-) 387 WP_001110179.1 hypothetical protein -
  UXQ48_RS09580 (UXQ48_09580) map 1955665..1956423 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  UXQ48_RS09585 (UXQ48_09585) - 1956954..1957940 (+) 987 WP_000999710.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23601.40 Da        Isoelectric Point: 5.3935

>NTDB_id=975282 UXQ48_RS09560 WP_341532650.1 1952687..1953316(-) (vraR) [Staphylococcus aureus strain BSN164]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRVESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=975282 UXQ48_RS09560 WP_341532650.1 1952687..1953316(-) (vraR) [Staphylococcus aureus strain BSN164]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGTAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTCATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment