Detailed information NTG0975283

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ48_RS09565
• Genome accession: NZ_CP151138
• Coordinates: 1953306..1954349 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN164
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1948306..1959349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ48_RS09535 (UXQ48_09535)	-	1948727..1949983 (-)	1257	WP_001795108.1	aminopeptidase	-
UXQ48_RS09540 (UXQ48_09540)	-	1949986..1950186 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXQ48_RS09545 (UXQ48_09545)	-	1950333..1950797 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ48_RS09550 (UXQ48_09550)	-	1950804..1951079 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ48_RS09555 (UXQ48_09555)	-	1951357..1952574 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ48_RS09560 (UXQ48_09560)	vraR	1952687..1953316 (-)	630	WP_341532650.1	two-component system response regulator VraR	Regulator
UXQ48_RS09565 (UXQ48_09565)	vraS	1953306..1954349 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ48_RS09570 (UXQ48_09570)	liaF	1954346..1955047 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ48_RS09575 (UXQ48_09575)	-	1955062..1955448 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ48_RS09580 (UXQ48_09580)	map	1955665..1956423 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ48_RS09585 (UXQ48_09585)	-	1956954..1957940 (+)	987	WP_000999710.1	aromatic acid exporter family protein	-
UXQ48_RS09590 (UXQ48_09590)	-	1958371..1958784 (-)	414	WP_001557448.1	hypothetical protein	-
UXQ48_RS09595 (UXQ48_09595)	-	1958813..1958923 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=975283 UXQ48_RS09565 WP_001017131.1 1953306..1954349(-) (vraS) [Staphylococcus aureus strain BSN164]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=975283 UXQ48_RS09565 WP_001017131.1 1953306..1954349(-) (vraS) [Staphylococcus aureus strain BSN164]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1