Detailed information NTG0097516

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R8474_RS09300
• Genome accession: NZ_AP026914
• Coordinates: 1832998..1834008 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900700003
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1827998..1839008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8474_RS09275 (PC0003_18250)	-	1829209..1829502 (-)	294	WP_000977368.1	hypothetical protein	-
R8474_RS09280 (PC0003_18260)	-	1829664..1830116 (+)	453	WP_000079148.1	universal stress protein	-
R8474_RS09285 (PC0003_18270)	-	1830151..1831539 (-)	1389	WP_081573898.1	Cof-type HAD-IIB family hydrolase	-
R8474_RS09290 (PC0003_18280)	-	1831605..1832567 (+)	963	WP_001124771.1	asparaginase	-
R8474_RS09295 (PC0003_18290)	-	1832596..1832934 (-)	339	WP_081573899.1	hypothetical protein	-
R8474_RS09300 (PC0003_18300)	ccpA	1832998..1834008 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R8474_RS09305 (PC0003_18310)	-	1834433..1835032 (-)	600	WP_000866724.1	response regulator transcription factor	-
R8474_RS09310 (PC0003_18320)	-	1835034..1836131 (-)	1098	WP_061714356.1	sensor histidine kinase	-
R8474_RS09315	-	1836131..1836868 (-)	738	WP_001820802.1	ABC transporter permease	-
R8474_RS09320 (PC0003_18340)	-	1836870..1837754 (-)	885	WP_000219358.1	ABC transporter ATP-binding protein	-
R8474_RS09325 (PC0003_18350)	-	1837741..1837935 (-)	195	WP_000820182.1	hypothetical protein	-
R8474_RS09330 (PC0003_18360)	-	1837932..1838138 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=97516 R8474_RS09300 WP_000990607.1 1832998..1834008(-) (ccpA) [Streptococcus pneumoniae strain PZ900700003]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=97516 R8474_RS09300 WP_000990607.1 1832998..1834008(-) (ccpA) [Streptococcus pneumoniae strain PZ900700003]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCCAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568