Detailed information NTG0973336

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: WAF13_RS29065
• Genome accession: NZ_CP150882
• Coordinates: 6046461..6047798 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain FI-26059
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 6041461..6052798

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WAF13_RS29040 (WAF13_29050)	pgeF	6041604..6042332 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
WAF13_RS29045 (WAF13_29055)	rluD	6042329..6043291 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
WAF13_RS29050 (WAF13_29060)	-	6043437..6044462 (+)	1026	WP_003094687.1	outer membrane protein assembly factor BamD	-
WAF13_RS29055 (WAF13_29065)	-	6044619..6044864 (+)	246	WP_014603563.1	PP0621 family protein	-
WAF13_RS29060 (WAF13_29070)	pilS	6044854..6046446 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
WAF13_RS29065 (WAF13_29075)	pilR	6046461..6047798 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
WAF13_RS29070 (WAF13_29080)	thiO	6047844..6048938 (-)	1095	WP_003094695.1	glycine oxidase ThiO	-
WAF13_RS29075 (WAF13_29085)	-	6049073..6049582 (+)	510	WP_015503652.1	Tfp pilus assembly protein FimT/FimU	-
WAF13_RS29080 (WAF13_29090)	-	6049688..6050194 (+)	507	WP_003094696.1	Tfp pilus assembly protein FimT/FimU	-
WAF13_RS29085 (WAF13_29095)	pilV	6050185..6050742 (+)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
WAF13_RS29090 (WAF13_29100)	pilW	6050739..6051563 (+)	825	WP_003094698.1	type 4a pilus minor pilin PilW	-
WAF13_RS29095 (WAF13_29105)	pilX	6051560..6052147 (+)	588	WP_003094700.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=973336 WAF13_RS29065 WP_003094694.1 6046461..6047798(+) (pilR) [Pseudomonas aeruginosa strain FI-26059]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=973336 WAF13_RS29065 WP_003094694.1 6046461..6047798(+) (pilR) [Pseudomonas aeruginosa strain FI-26059]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTAGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384