Detailed information NTG0973210

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: WMY90_RS01300
• Genome accession: NZ_CP150875
• Coordinates: 246165..247166 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain TCI125
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 241165..252166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WMY90_RS01280 (WMY90_01280)	smpB	242271..242735 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
WMY90_RS01285 (WMY90_01285)	-	242889..244295 (+)	1407	WP_022096975.1	Cof-type HAD-IIB family hydrolase	-
WMY90_RS01290 (WMY90_01290)	-	244297..244662 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
WMY90_RS01295 (WMY90_01295)	-	244765..245850 (-)	1086	WP_011225703.1	Xaa-Pro peptidase family protein	-
WMY90_RS01300 (WMY90_01300)	ccpA	246165..247166 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
WMY90_RS01305 (WMY90_01305)	-	247225..247422 (+)	198	WP_014608125.1	hypothetical protein	-
WMY90_RS01310 (WMY90_01310)	-	247528..248292 (+)	765	WP_004197425.1	MmcQ/YjbR family DNA-binding protein	-
WMY90_RS01315 (WMY90_01315)	-	248307..249422 (+)	1116	WP_022096976.1	glycerate kinase	-
WMY90_RS01320 (WMY90_01320)	-	249461..249916 (-)	456	WP_022096977.1	YueI family protein	-
WMY90_RS01325 (WMY90_01325)	eno	250125..251429 (+)	1305	WP_022096978.1	surface-displayed alpha-enolase	-
WMY90_RS01330 (WMY90_01330)	-	251581..251765 (-)	185	Protein_251	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=973210 WMY90_RS01300 WP_004197422.1 246165..247166(+) (ccpA) [Streptococcus thermophilus strain TCI125]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=973210 WMY90_RS01300 WP_004197422.1 246165..247166(+) (ccpA) [Streptococcus thermophilus strain TCI125]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCACCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGTCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547