Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   AAAF57_RS09335 Genome accession   NZ_CP150847
Coordinates   2018191..2018928 (-) Length   245 a.a.
NCBI ID   WP_002889752.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS5     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2013191..2023928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAAF57_RS09310 (AAAF57_09355) - 2013558..2014328 (-) 771 WP_038675188.1 membrane protein -
  AAAF57_RS09315 (AAAF57_09360) - 2014333..2015205 (-) 873 WP_038675187.1 ABC transporter ATP-binding protein -
  AAAF57_RS09320 (AAAF57_09365) - 2015198..2015617 (-) 420 WP_052124395.1 Msa family membrane protein -
  AAAF57_RS09325 (AAAF57_09370) - 2015742..2016482 (-) 741 WP_060775842.1 amino acid transporter -
  AAAF57_RS09330 (AAAF57_09375) - 2016857..2018194 (-) 1338 WP_155164425.1 GHKL domain-containing protein -
  AAAF57_RS09335 (AAAF57_09380) comE/blpR 2018191..2018928 (-) 738 WP_002889752.1 response regulator transcription factor Regulator
  AAAF57_RS09340 (AAAF57_09385) - 2018944..2019420 (-) 477 WP_002889751.1 LytTR family DNA-binding domain-containing protein -
  AAAF57_RS09345 (AAAF57_09390) - 2019474..2019872 (+) 399 WP_038675182.1 hypothetical protein -
  AAAF57_RS09350 (AAAF57_09395) - 2020179..2022746 (-) 2568 WP_195520201.1 SEC10/PgrA surface exclusion domain-containing protein -
  AAAF57_RS09355 (AAAF57_09400) - 2023087..2023635 (+) 549 WP_229103963.1 VanZ family protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28467.55 Da        Isoelectric Point: 7.1603

>NTDB_id=972993 AAAF57_RS09335 WP_002889752.1 2018191..2018928(-) (comE/blpR) [Streptococcus salivarius strain KSS5]
MLNIFVLEDDFFQQTRIETAIKKCMSDNKMRYRYLEVFGKPQQLLDAIKETGNHQFFFLDIEIKGDKKRGMEIAREIREK
DPSASIVFVTTHSEFMPVTYSYRVSALDFIDKGLSDQDYQEAISSVLIHATGSVNKTIGEDSFCFKSEHSQIQVPFSDIL
YFETSPTIHKVILTTKKGHMEFYGKVSDIAKADKRLYQSHRSYVVNPENIIRIDKSNHTVFFENDESCFVSRMKLKGLVE
RITLR

Nucleotide


Download         Length: 738 bp        

>NTDB_id=972993 AAAF57_RS09335 WP_002889752.1 2018191..2018928(-) (comE/blpR) [Streptococcus salivarius strain KSS5]
ATGTTAAATATTTTTGTTCTAGAAGATGATTTTTTTCAGCAAACTCGTATTGAGACAGCGATTAAGAAATGTATGTCTGA
TAATAAAATGAGGTATAGGTATTTAGAAGTCTTTGGTAAGCCTCAACAGTTGTTAGATGCAATTAAAGAGACAGGAAATC
ATCAATTTTTCTTTCTTGATATTGAAATTAAAGGAGATAAAAAGAGAGGAATGGAGATTGCGCGTGAAATCCGTGAAAAA
GATCCTAGTGCGTCGATTGTCTTTGTGACGACTCACTCAGAATTTATGCCAGTCACCTACAGTTACCGTGTATCTGCTTT
GGACTTTATCGACAAAGGGTTAAGTGATCAAGATTATCAGGAAGCTATTTCGTCTGTTTTGATACATGCTACTGGTAGTG
TTAATAAAACAATAGGTGAAGATTCATTTTGTTTTAAATCAGAACATTCCCAAATACAAGTTCCTTTTTCAGATATTCTT
TATTTTGAGACCTCACCTACGATTCATAAGGTAATTTTAACGACGAAGAAAGGCCATATGGAATTTTATGGTAAAGTTTC
AGATATTGCGAAGGCAGACAAAAGACTCTACCAAAGTCATAGATCTTATGTAGTGAATCCAGAGAATATTATTCGTATTG
ACAAATCAAATCATACTGTTTTCTTTGAAAATGATGAATCTTGTTTTGTATCTCGTATGAAATTAAAAGGTTTAGTTGAG
AGGATTACTTTGAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

55.23

97.551

0.539
  comE/comE1 Streptococcus equinus JB1

50.209

97.551

0.49
  comE/comE2 Streptococcus equinus JB1

41.597

97.143

0.404

Multiple sequence alignment