Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   WOC70_RS12980 Genome accession   NZ_CP150742
Coordinates   2600918..2601604 (+) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain TUM22707     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2595918..2606604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC70_RS12945 (WOC70_12945) yqeH 2596445..2597545 (+) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -
  WOC70_RS12950 (WOC70_12950) aroE 2597559..2598365 (+) 807 WP_000666757.1 shikimate dehydrogenase -
  WOC70_RS12955 (WOC70_12955) yhbY 2598369..2598659 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  WOC70_RS12960 (WOC70_12960) nadD 2598662..2599231 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  WOC70_RS12965 (WOC70_12965) yqeK 2599221..2599805 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  WOC70_RS12970 (WOC70_12970) rsfS 2599806..2600159 (+) 354 WP_001088020.1 ribosome silencing factor -
  WOC70_RS12975 (WOC70_12975) - 2600162..2600878 (+) 717 WP_000084830.1 class I SAM-dependent methyltransferase -
  WOC70_RS12980 (WOC70_12980) comEA 2600918..2601604 (+) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  WOC70_RS12985 (WOC70_12985) - 2601696..2602157 (+) 462 WP_000439693.1 ComE operon protein 2 -
  WOC70_RS12990 (WOC70_12990) - 2602162..2604362 (+) 2201 Protein_2519 DNA internalization-related competence protein ComEC/Rec2 -
  WOC70_RS12995 (WOC70_12995) holA 2604419..2605393 (+) 975 WP_001282563.1 DNA polymerase III subunit delta -
  WOC70_RS13000 (WOC70_13000) rpsT 2605438..2605689 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=971581 WOC70_RS12980 WP_001802022.1 2600918..2601604(+) (comEA) [Staphylococcus aureus strain TUM22707]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=971581 WOC70_RS12980 WP_001802022.1 2600918..2601604(+) (comEA) [Staphylococcus aureus strain TUM22707]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974

Multiple sequence alignment