Detailed information NTG0970948

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: UXR81_RS00305
• Genome accession: NZ_CP150651
• Coordinates: 65596..67224 (-)
• Length: 542 a.a.
• NCBI ID: WP_001186602.1
• Uniprot ID: Q9XB94
• Organism: Staphylococcus aureus strain BSN213
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	47268..68595	65596..67224	within	0

Gene organization within MGE regions

Location: 47268..68595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR81_RS00210 (UXR81_00210)	mecA	47268..49277 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
UXR81_RS00215 (UXR81_00215)	mecR1	49374..51131 (+)	1758	WP_000952923.1	beta-lactam sensor/signal transducer MecR1	-
UXR81_RS00220 (UXR81_00220)	mecI	51131..51502 (+)	372	WP_000369214.1	mecA-type methicillin resistance repressor MecI	-
UXR81_RS00225 (UXR81_00225)	psm-mec	51587..51655 (-)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
UXR81_RS00230 (UXR81_00230)	-	51989..53119 (+)	1131	WP_010922808.1	ROK family transcriptional regulator	-
UXR81_RS00235 (UXR81_00235)	cstB	53233..54567 (-)	1335	Protein_44	persulfide dioxygenase-sulfurtransferase CstB	-
UXR81_RS00240 (UXR81_00240)	-	54600..55664 (-)	1065	WP_000438836.1	DsrE/DsrF/DrsH-like family protein	-
UXR81_RS00245 (UXR81_00245)	cstR	55800..56060 (+)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
UXR81_RS00250 (UXR81_00250)	-	56060..56698 (+)	639	Protein_47	sulfite exporter TauE/SafE family protein	-
UXR81_RS00255 (UXR81_00255)	-	57043..57705 (-)	663	WP_001092058.1	class I SAM-dependent methyltransferase	-
UXR81_RS00260 (UXR81_00260)	erm(A)	58201..58932 (+)	732	WP_001072201.1	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	-
UXR81_RS00265 (UXR81_00265)	-	59058..59840 (-)	783	WP_000067268.1	aminoglycoside nucleotidyltransferase ANT(9)-Ia	-
UXR81_RS00270 (UXR81_00270)	-	59991..60368 (-)	378	WP_000361059.1	DUF6262 family protein	-
UXR81_RS00275 (UXR81_00275)	-	60375..62267 (-)	1893	WP_001557544.1	site-specific integrase	-
UXR81_RS00280 (UXR81_00280)	-	62264..63349 (-)	1086	WP_000868132.1	tyrosine-type recombinase/integrase	-
UXR81_RS00285 (UXR81_00285)	-	63468..63785 (-)	318	WP_000659050.1	JAB domain-containing protein	-
UXR81_RS00290 (UXR81_00290)	-	63806..64312 (-)	507	WP_001092169.1	DUF1643 domain-containing protein	-
UXR81_RS00295 (UXR81_00295)	-	64330..64641 (-)	312	WP_000700853.1	DUF960 family protein	-
UXR81_RS00300 (UXR81_00300)	-	64728..65078 (-)	351	WP_000859155.1	SAUGI family uracil-DNA glycosylase inhibitor	-
UXR81_RS00305 (UXR81_00305)	ccrB	65596..67224 (-)	1629	WP_001186602.1	recombinase family protein	Machinery gene
UXR81_RS00310 (UXR81_00310)	ccrA	67246..68595 (-)	1350	WP_000815646.1	recombinase family protein	Machinery gene

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62664.84 Da
• Isoelectric Point: 9.8600

>NTDB_id=970948 UXR81_RS00305 WP_001186602.1 65596..67224(-) (ccrB) [Staphylococcus aureus strain BSN213]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide

• Length: 1629 bp

>NTDB_id=970948 UXR81_RS00305 WP_001186602.1 65596..67224(-) (ccrB) [Staphylococcus aureus strain BSN213]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

3D structure

• AlphaFold DB: Q9XB94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	100	100	1