Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACJWMD_RS02350 Genome accession   NZ_CP177182
Coordinates   449676..450428 (+) Length   250 a.a.
NCBI ID   WP_002886759.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD6060     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 444676..455428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS02335 - 445023..445715 (+) 693 WP_002886755.1 DUF6287 domain-containing protein -
  ACJWMD_RS02340 - 445780..446070 (+) 291 WP_002885564.1 hypothetical protein -
  ACJWMD_RS02345 - 446357..449473 (+) 3117 WP_002886757.1 SH3 domain-containing protein -
  ACJWMD_RS02350 comE/blpR 449676..450428 (+) 753 WP_002886759.1 response regulator transcription factor Regulator
  ACJWMD_RS02355 - 450563..451228 (+) 666 WP_002886760.1 DUF6287 domain-containing protein -
  ACJWMD_RS02360 comE/blpR 451476..452210 (+) 735 WP_002886762.1 response regulator transcription factor Regulator
  ACJWMD_RS02365 - 452207..453526 (+) 1320 WP_002886763.1 sensor histidine kinase -
  ACJWMD_RS02370 - 453624..454190 (+) 567 WP_002886764.1 transcriptional regulator -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28684.11 Da        Isoelectric Point: 5.3920

>NTDB_id=969809 ACJWMD_RS02350 WP_002886759.1 449676..450428(+) (comE/blpR) [Streptococcus salivarius strain MRD6060]
MLDIFVLEEDYFQQARLEDAIHKSKQIYILRIGKVDLYDKPNQLLERITERGSHLLFFLDIGSDSDVEGGILVAQQIRER
DPYASIVFITAHPELLPSTFQYRLAALDFIDKNLPDIEYEDRIISDIGLALSKNGLSQIECAFTIDTKNATIQVPFHKIL
YFETSPTVHKVILHTTEEQIEFYGQLSKVVKQDCRLYKCHKSFVVNPENIVRLDKELGVIYFENGESCLVSKAKQKEIVA
KMLVPKSMAV

Nucleotide


Download         Length: 753 bp        

>NTDB_id=969809 ACJWMD_RS02350 WP_002886759.1 449676..450428(+) (comE/blpR) [Streptococcus salivarius strain MRD6060]
ATGTTAGATATTTTTGTTTTAGAAGAAGATTATTTTCAACAAGCTCGTCTTGAGGATGCTATCCACAAGTCTAAACAAAT
ATATATTTTAAGAATTGGGAAGGTTGATTTATACGATAAACCCAATCAATTATTAGAGCGTATTACGGAAAGGGGCTCGC
ATTTACTGTTTTTTCTAGATATTGGATCTGACAGTGATGTCGAAGGGGGAATATTGGTTGCTCAACAGATTCGTGAGCGA
GATCCGTATGCAAGTATTGTTTTCATCACAGCACATCCCGAACTCCTACCTTCAACCTTTCAGTATCGCTTAGCTGCACT
TGATTTTATTGACAAGAATTTGCCTGATATTGAATATGAAGATAGGATTATTTCTGATATTGGATTAGCACTTTCTAAAA
ATGGTCTGAGCCAAATAGAGTGTGCTTTTACTATAGATACAAAGAATGCAACTATACAAGTTCCTTTTCATAAGATTCTC
TATTTTGAAACATCTCCAACGGTTCATAAGGTAATTCTTCATACAACAGAAGAGCAAATTGAGTTCTATGGTCAATTATC
AAAAGTTGTAAAACAAGATTGCAGACTATATAAATGCCATAAATCATTTGTTGTAAATCCCGAAAACATTGTGAGATTGG
ACAAAGAATTAGGTGTTATTTATTTTGAAAACGGAGAGTCATGCTTGGTTTCGAAAGCTAAACAAAAAGAGATTGTTGCT
AAGATGCTTGTTCCAAAATCCATGGCAGTTTGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

45.679

97.2

0.444
  comE/comE1 Streptococcus equinus JB1

42.149

96.8

0.408