Detailed information NTG0096857

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AACH38_RS08770
• Genome accession: NZ_AP028992
• Coordinates: 1820989..1821978 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain TUM19957
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1815989..1826978

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AACH38_RS08755 (TUM19957_16740)	acsA	1817190..1818896 (-)	1707	WP_000862105.1	acetate--CoA ligase	-
AACH38_RS08760 (TUM19957_16750)	-	1819065..1819697 (+)	633	WP_001016007.1	GNAT family N-acetyltransferase	-
AACH38_RS08765 (TUM19957_16760)	-	1819722..1820891 (+)	1170	WP_001184003.1	acetoin utilization protein AcuC	-
AACH38_RS08770 (TUM19957_16770)	ccpA	1820989..1821978 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
AACH38_RS08775	-	1822051..1822164 (-)	114	WP_001788994.1	hypothetical protein	-
AACH38_RS08780 (TUM19957_16780)	-	1822517..1823608 (-)	1092	WP_000066379.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
AACH38_RS08785	-	1824063..1824146 (-)	84	WP_031789490.1	hypothetical protein	-
AACH38_RS08790 (TUM19957_16790)	-	1824302..1825660 (-)	1359	WP_000193930.1	hypothetical protein	-
AACH38_RS08795 (TUM19957_16800)	-	1825734..1826225 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=96857 AACH38_RS08770 WP_000219066.1 1820989..1821978(-) (ccpA) [Staphylococcus aureus strain TUM19957]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=96857 AACH38_RS08770 WP_000219066.1 1820989..1821978(-) (ccpA) [Staphylococcus aureus strain TUM19957]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAAGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGTCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGTAATCTTCCAGATGCTATA
TTATGTATTAGTGACGAAGAAGCTATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGTTTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAATGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462