Detailed information NTG0967917

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ACK2I7_RS08070
• Genome accession: NZ_CP176632
• Coordinates: 1632998..1635559 (-)
• Length: 853 a.a.
• NCBI ID: WP_057489838.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain SFAD 40
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1627998..1640559

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACK2I7_RS08045	ruvA	1628079..1628669 (-)	591	WP_021002202.1	Holliday junction branch migration protein RuvA	Machinery gene
ACK2I7_RS08050	-	1628831..1629340 (+)	510	WP_003026648.1	helix-turn-helix domain-containing protein	-
ACK2I7_RS08055	hexB	1629723..1631669 (-)	1947	WP_003026650.1	DNA mismatch repair endonuclease MutL	Machinery gene
ACK2I7_RS08060	brsR	1631914..1632354 (+)	441	WP_411353963.1	LytTR family DNA-binding domain-containing protein	Regulator
ACK2I7_RS08065	-	1632351..1632809 (+)	459	WP_021002204.1	DUF3021 domain-containing protein	-
ACK2I7_RS08070	hexA	1632998..1635559 (-)	2562	WP_057489838.1	DNA mismatch repair protein MutS	Machinery gene
ACK2I7_RS08075	argR	1635722..1636162 (-)	441	WP_003027809.1	arginine repressor	-
ACK2I7_RS08080	argS	1636266..1637954 (+)	1689	WP_021002206.1	arginine--tRNA ligase	-
ACK2I7_RS08085	nrdI	1638009..1638464 (-)	456	WP_021002207.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
ACK2I7_RS08090	-	1638540..1639049 (-)	510	WP_003027812.1	hypothetical protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 96049.80 Da
• Isoelectric Point: 5.0000

>NTDB_id=967917 ACK2I7_RS08070 WP_057489838.1 1632998..1635559(-) (hexA) [Streptococcus anginosus strain SFAD 40]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAINAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLSGIYGLAYMDVGTGEFQVTSLSDFNM
VCGEIRNLRAREVVLGYELSEMERQVLEIQMNLLLSQVETTFDDVQLLGKDLSPLERQVAGKLLQYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLSDTLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILKGIDSPVLEDLIAKLDEIPELANLIQLAISP
DAPNVITEGNIIKTGFDETLDKYRVVMRDGTSWIADIEAKEREASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTLATVDVLQSFAAVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNQTGAKTLFATHYHEL
TELSTSLTQLENVHVATLEKDGQVTFLHKIEVGPADKSYGIHVAKIAGLPNDLLTRADQILTRLESQANEKSSFGISNTL
PADAREKNQVAEQMSLFTETTESPILDELRQLDIYNMTPMEVMLAVAEIKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=967917 ACK2I7_RS08070 WP_057489838.1 1632998..1635559(-) (hexA) [Streptococcus anginosus strain SFAD 40]
ATGACAAAAGAAAAACTATCTCCGGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGCTATT
TCGTATGGGAGATTTTTATGAATTATTCTATGAAGATGCGATCAATGCAGCACAGATTTTAGAAATTGCTCTGACTAGCC
GTAATAAAAATTCGGAAAATCCAATCCCGATGGCAGGAGTTCCCTACCATTCGGTGCAACAGTATATTGATGTTTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGCGAAGTAGT
ACAGGTGATTACGCCGGGGACAGTAGTTGATTCTTCAAAACCAGACAGTCAGAATAACTTTTTAGTGGCTTTGGATAAGC
TGTCAGGTATATATGGGCTGGCTTATATGGATGTGGGAACGGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATG
GTCTGTGGAGAAATCCGAAACTTGCGAGCGCGTGAAGTGGTCTTAGGGTATGAATTGTCTGAAATGGAGCGCCAAGTATT
GGAGATTCAAATGAATCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCGC
CGCTAGAGCGCCAAGTAGCTGGAAAGTTATTACAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGATTACTCAACTATGGCAAGTCTGGATTTAACAGAGAATGCTCG
GACAGGAAAGAAGCACGGGAGCCTTTATTGGCTGATGGATGAGACTAAGACAGCTATGGGAACACGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGAATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAACGCAGTGACTTATCAGACACTCTCAAAGGAGTGTATGATATTGAGCGTTTAGCCAGTCGGGTTTCGTTTGGCAAGAC
CAATCCGAAAGATCTATTACAACTTGCTGCGACATTGAGTCATGTACCACAAATTAAGGGAATCTTAAAAGGAATTGACA
GCCCAGTTTTGGAAGATTTGATTGCCAAATTGGATGAAATTCCTGAATTGGCAAACTTGATTCAGTTGGCAATTTCGCCG
GATGCTCCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACCTTGGACAAGTATCGAGTGGTCAT
GCGAGATGGAACGAGCTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAGCTAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTCACCAATTCTCAGCTTGAACATGTTCCCAGTCATTTTTTCCGCAAGGCA
ACTTTGAAAAATTCGGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGTGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAATATATCAAACGCCTGCAATCCTTGGCGC
AAACTCTGGCAACGGTTGATGTGCTGCAAAGCTTTGCAGCTGTAGCAGAAAAGCAACATTTTGTGAGACCAGAATTTATT
GAGCAGCGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTCGTAGAAAAAGTTATGGGTGCACAAACCTATATTCCTAA
TAGCATTTCAATGGATGAGAATGTTAATGTTCAGCTAATTACAGGCCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCGATTATTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCCGAAAGTGCCCAATTGCCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCTGATGACTTGGTTTCTGGACAATCAACCTTTATGGTGGAAATGATGGAAGCGAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTCATTCTTTTTGATGAGTTAGGAAGAGGAACAGCTACCTATGATGGCATGG
CGCTTGCTCAAGCTATTATTGAGTATATTCACAATCAGACAGGAGCCAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGCAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAGGTTGGACCTGCTGATAAATCTTATGGGATTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGGATCAAATATTGACACGATTAGAAAGCCAAGCAAATGAGAAGTCATCTTTTGGCATCTCTAATACATTG
CCTGCGGATGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTACAGAAACAACTGAATCACCTATTTTAGA
CGAGTTGCGCCAGTTGGACATTTATAATATGACCCCAATGGAAGTGATGTTGGCTGTGGCAGAGATAAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (255-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.788	100	0.768
mutS	Pseudomonas stutzeri strain ATCC 17587	36.121	100	0.365