Detailed information NTG0096241

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AABJ45_RS10070
• Genome accession: NZ_AP028611
• Coordinates: 1971708..1972607 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904858.1
• Uniprot ID: A0A0H2URY1
• Organism: Streptococcus pneumoniae strain Sep6
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1966708..1977607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABJ45_RS10050 (TKY121527_19870)	rsmA	1967462..1968334 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
AABJ45_RS10055 (TKY121527_19880)	-	1968465..1968773 (-)	309	WP_000333257.1	hypothetical protein	-
AABJ45_RS10060 (TKY121527_19890)	-	1968766..1969407 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
AABJ45_RS10065 (TKY121527_19900)	-	1969409..1971439 (-)	2031	WP_172955123.1	bacteriocin-associated integral membrane family protein	-
AABJ45_RS10070 (TKY121527_19910)	comR	1971708..1972607 (-)	900	WP_000904858.1	helix-turn-helix transcriptional regulator	Regulator
AABJ45_RS10075 (TKY121527_19920)	rnmV	1972679..1973239 (-)	561	WP_000660004.1	ribonuclease M5	-
AABJ45_RS10080 (TKY121527_19930)	-	1973239..1974012 (-)	774	WP_000575607.1	TatD family hydrolase	-
AABJ45_RS10085 (TKY121527_19940)	-	1974317..1975210 (-)	894	WP_000226469.1	DUF1542 domain-containing protein	-
AABJ45_RS10090 (TKY121527_19950)	rpmH	1975494..1975628 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
AABJ45_RS10095 (TKY121527_19960)	-	1976036..1976989 (+)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35409.11 Da
• Isoelectric Point: 4.7119

>NTDB_id=96241 AABJ45_RS10070 WP_000904858.1 1971708..1972607(-) (comR) [Streptococcus pneumoniae strain Sep6]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=96241 AABJ45_RS10070 WP_000904858.1 1971708..1972607(-) (comR) [Streptococcus pneumoniae strain Sep6]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

3D structure

• AlphaFold DB: A0A0H2URY1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361