Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   WIR73_RS12550 Genome accession   NZ_CP149750
Coordinates   2717535..2718242 (-) Length   235 a.a.
NCBI ID   WP_021366255.1    Uniprot ID   A0A069AVD9
Organism   Clostridioides difficile strain Z1322HCD0033     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2712535..2723242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WIR73_RS12535 (WIR73_12535) - 2712815..2713285 (-) 471 WP_009888463.1 VOC family protein -
  WIR73_RS12540 (WIR73_12540) - 2714025..2714414 (-) 390 WP_003426867.1 BlaI/MecI/CopY family transcriptional regulator -
  WIR73_RS12545 (WIR73_12545) - 2716084..2717490 (-) 1407 WP_074140180.1 HAMP domain-containing sensor histidine kinase -
  WIR73_RS12550 (WIR73_12550) scnR 2717535..2718242 (-) 708 WP_021366255.1 response regulator transcription factor Regulator
  WIR73_RS12555 (WIR73_12555) - 2718404..2719327 (+) 924 WP_025985748.1 ATP-binding cassette domain-containing protein -
  WIR73_RS12560 (WIR73_12560) - 2719327..2720088 (+) 762 WP_003439185.1 ABC transporter permease -
  WIR73_RS12565 (WIR73_12565) - 2720100..2720837 (+) 738 WP_074140179.1 ABC transporter permease -
  WIR73_RS12570 (WIR73_12570) - 2721754..2722023 (+) 270 WP_003426848.1 DUF3795 domain-containing protein -
  WIR73_RS12575 (WIR73_12575) cdd1 2722241..2722486 (-) 246 WP_009888450.1 protein Cdd1 -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26730.20 Da        Isoelectric Point: 6.1479

>NTDB_id=961231 WIR73_RS12550 WP_021366255.1 2717535..2718242(-) (scnR) [Clostridioides difficile strain Z1322HCD0033]
MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIP
VIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKEGQEIS
LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLITVRGLGYKLMIN

Nucleotide


Download         Length: 708 bp        

>NTDB_id=961231 WIR73_RS12550 WP_021366255.1 2717535..2718242(-) (scnR) [Clostridioides difficile strain Z1322HCD0033]
ATGGAGTCAATAAAAGATAAAAAAATACTTGTGGTTGATGACCACAAGGAATTATTAAAAATGATAGATGAAATCCTGAG
AAAAGAGGGATTTAGTAGAGTATTTTTAGCATCAAGTTATGAGGAAGCTGTTAGGGTATTTAGAAATGTAAAGCCAGATT
GTGCAATTTTAGATGTTGTATTGCCAGATGGAGATGGTTTTTCTATTATGAGAAAAATTAGAGAGACATCTAAAATACCA
GTGATTTTTCTCTCTGCAAGAGGTGAAGATGAAGATAGATTGATTGGTTTGGGCTTAGGGGCTGACGATTATATAGTAAA
GCCATTTTTACCAAAGGAACTTACTTTAAGGCTTGTGGGTATATTAAATCGTGTATATGTGCCTATAGAAGAAGAGGAGT
TGCCAGTATTTAAACTGGGAGATTCTGTTGTTGTGAATTTAAATAGTGCATGTGTTGAGAAAGAAGGGCAAGAGATTTCT
TTAACAGCTAAAGAGCATTCGTTGCTTTTAAAGTTGTATGAAAATAAAGGGAGAATTGTTACTAATGATTCACTATGTCA
AGCCATTTGGGGAGATGATATGTATGGATATGAAAATACCCTTATGGTTCATGTTAGAAGGGTTAGAGAGAAGATAGAAA
AAACTCCATCTACACCTAAACATCTTATTACAGTAAGAGGTCTTGGATATAAGTTGATGATTAATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-232)

Response regulator receiver domain (Response_reg)

(9-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A069AVD9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

48.918

98.298

0.481
  micA Streptococcus pneumoniae Cp1015

40

100

0.4
  vicR Streptococcus mutans UA159

38.362

98.723

0.379