Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   WIS25_RS14465 Genome accession   NZ_CP149715
Coordinates   3253226..3253933 (-) Length   235 a.a.
NCBI ID   WP_009888460.1    Uniprot ID   A0A9Q8EBL8
Organism   Clostridioides difficile strain Z1322HCD0115     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 3248226..3258933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WIS25_RS14450 (WIS25_14450) - 3248555..3249025 (-) 471 WP_009888463.1 VOC family protein -
  WIS25_RS14455 (WIS25_14455) - 3249759..3250148 (-) 390 WP_003426867.1 BlaI/MecI/CopY family transcriptional regulator -
  WIS25_RS14460 (WIS25_14460) - 3251775..3253181 (-) 1407 WP_159376471.1 HAMP domain-containing sensor histidine kinase -
  WIS25_RS14465 (WIS25_14465) scnR 3253226..3253933 (-) 708 WP_009888460.1 response regulator transcription factor Regulator
  WIS25_RS14470 (WIS25_14470) - 3254095..3255018 (+) 924 WP_025985748.1 ATP-binding cassette domain-containing protein -
  WIS25_RS14475 (WIS25_14475) - 3255018..3255779 (+) 762 WP_009902075.1 ABC transporter permease -
  WIS25_RS14480 (WIS25_14480) - 3255791..3256528 (+) 738 WP_003439186.1 ABC transporter permease -
  WIS25_RS14485 (WIS25_14485) - 3257406..3257675 (+) 270 WP_003426848.1 DUF3795 domain-containing protein -
  WIS25_RS14490 (WIS25_14490) cdd1 3257893..3258138 (-) 246 WP_009888450.1 protein Cdd1 -
  WIS25_RS14495 (WIS25_14495) - 3258450..3258830 (-) 381 WP_016728653.1 BlaI/MecI/CopY family transcriptional regulator -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26716.17 Da        Isoelectric Point: 6.1467

>NTDB_id=960953 WIS25_RS14465 WP_009888460.1 3253226..3253933(-) (scnR) [Clostridioides difficile strain Z1322HCD0115]
MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIP
VIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLITVRGLGYKLMIN

Nucleotide


Download         Length: 708 bp        

>NTDB_id=960953 WIS25_RS14465 WP_009888460.1 3253226..3253933(-) (scnR) [Clostridioides difficile strain Z1322HCD0115]
ATGGAGTCAATAAAAGATAAAAAAATACTTGTGGTTGATGACCACAAGGAATTATTAAAAATGATAGATGAAATCCTGAG
AAAAGAGGGATTTAGTAGAGTATTTTTAGCATCAAGTTATGAGGAAGCTGTTAGGGTATTTAGAAATGTAAAGCCAGATT
GTGCAATTTTAGATGTTGTATTGCCAGATGGAGATGGTTTTTCTATTATGAGAAAAATTAGAGAGACATCTAAAATACCA
GTGATTTTTCTCTCTGCAAGAGGTGAAGATGAAGATAGATTGATTGGTTTGGGCTTAGGGGCTGACGATTATATAGTAAA
GCCATTTTTACCAAAGGAACTTACTTTAAGGCTTGTGGGTATATTAAATCGTGTATATGTGCCTATAGAAGAAGAGGAGT
TGCCAGTATTTAAACTGGGAGATTCTGTTGTTGTGAATTTAAATAGTGCATGTGTTGAGAAAGATGGGCAAGAGATTTCT
TTAACAGCTAAAGAGCATTCGTTGCTTTTAAAGTTGTATGAAAATAAAGGGAGAATTGTTACTAATGATTCACTATGTCA
AGCCATTTGGGGAGATGATATGTATGGATATGAAAATACCCTTATGGTTCATGTTAGAAGAGTTAGAGAGAAGATAGAAA
AAACTCCATCTACACCTAAACATCTTATTACAGTAAGAGGTCTTGGATATAAGTTGATGATTAATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-232)

Response regulator receiver domain (Response_reg)

(9-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

48.918

98.298

0.481
  micA Streptococcus pneumoniae Cp1015

40

100

0.4
  vicR Streptococcus mutans UA159

38.362

98.723

0.379