Detailed information NTG0096002

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AABA19_RS09460
• Genome accession: NZ_AP028609
• Coordinates: 1849251..1850150 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904858.1
• Uniprot ID: A0A0H2URY1
• Organism: Streptococcus pneumoniae strain Sep4
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1844251..1855150

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA19_RS09440 (TKY121806_18540)	rsmA	1844900..1845772 (-)	873	WP_001216869.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
AABA19_RS09445	-	1846023..1846316 (-)	294	Protein_1850	hypothetical protein	-
AABA19_RS09450 (TKY121806_18560)	-	1846309..1846950 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
AABA19_RS09455 (TKY121806_18570)	-	1846952..1848982 (-)	2031	WP_338171996.1	bacteriocin-associated integral membrane family protein	-
AABA19_RS09460 (TKY121806_18580)	comR	1849251..1850150 (-)	900	WP_000904858.1	helix-turn-helix transcriptional regulator	Regulator
AABA19_RS09465 (TKY121806_18590)	rnmV	1850222..1850782 (-)	561	WP_000660004.1	ribonuclease M5	-
AABA19_RS09470 (TKY121806_18600)	-	1850782..1851555 (-)	774	WP_000575607.1	TatD family hydrolase	-
AABA19_RS09475 (TKY121806_18610)	-	1851860..1852831 (-)	972	Protein_1856	DUF1542 domain-containing protein	-
AABA19_RS09480 (TKY121806_18620)	rpmH	1853037..1853171 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
AABA19_RS09485 (TKY121806_18630)	-	1853316..1854530 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
AABA19_RS09490	-	1854686..1854980 (-)	295	Protein_1859	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35409.11 Da
• Isoelectric Point: 4.7119

>NTDB_id=96002 AABA19_RS09460 WP_000904858.1 1849251..1850150(-) (comR) [Streptococcus pneumoniae strain Sep4]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=96002 AABA19_RS09460 WP_000904858.1 1849251..1850150(-) (comR) [Streptococcus pneumoniae strain Sep4]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

3D structure

• AlphaFold DB: A0A0H2URY1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361