Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACI3MU_RS12310 Genome accession   NZ_CP173484
Coordinates   2332310..2332966 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 98221     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2327310..2337966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI3MU_RS12280 (ACI3MU_12280) yecA 2328562..2329227 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  ACI3MU_RS12300 (ACI3MU_12300) pgsA 2329876..2330424 (-) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACI3MU_RS12305 (ACI3MU_12305) uvrC 2330481..2332313 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACI3MU_RS12310 (ACI3MU_12310) letA 2332310..2332966 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACI3MU_RS12315 (ACI3MU_12315) - 2333108..2333179 (+) 72 Protein_2269 transcriptional regulator -
  ACI3MU_RS12320 (ACI3MU_12320) yecU 2333262..2333438 (+) 177 WP_000590347.1 protein YecU -
  ACI3MU_RS12325 (ACI3MU_12325) yecF 2333425..2333649 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACI3MU_RS12330 (ACI3MU_12330) sdiA 2333716..2334438 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  ACI3MU_RS12335 (ACI3MU_12335) tcyN 2334668..2335420 (-) 753 WP_001272987.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACI3MU_RS12340 (ACI3MU_12340) tcyL 2335417..2336085 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACI3MU_RS12345 (ACI3MU_12345) dcyD 2336100..2337086 (-) 987 WP_001128219.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=959710 ACI3MU_RS12310 WP_000611335.1 2332310..2332966(-) (letA) [Escherichia coli strain 98221]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=959710 ACI3MU_RS12310 WP_000611335.1 2332310..2332966(-) (letA) [Escherichia coli strain 98221]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486