Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACI3MI_RS03740 Genome accession   NZ_CP173479
Coordinates   462788..463378 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 98223     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 457788..468378
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI3MI_RS03725 (ACI3MI_03725) uhpT 458428..459819 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  ACI3MI_RS03730 (ACI3MI_03730) uhpC 459957..461276 (-) 1320 WP_064221540.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  ACI3MI_RS03735 (ACI3MI_03735) uhpB 461286..462788 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  ACI3MI_RS03740 (ACI3MI_03740) letA 462788..463378 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  ACI3MI_RS03745 (ACI3MI_03745) ilvN 463453..463743 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  ACI3MI_RS03750 (ACI3MI_03750) ilvB 463747..465435 (-) 1689 WP_061348785.1 acetolactate synthase large subunit -
  ACI3MI_RS03755 (ACI3MI_03755) ivbL 465541..465639 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  ACI3MI_RS03760 (ACI3MI_03760) tisB 466204..466293 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  ACI3MI_RS03765 (ACI3MI_03765) ysdE 466417..466491 (-) 75 WP_211180519.1 protein YsdE -
  ACI3MI_RS03770 (ACI3MI_03770) emrD 466573..467757 (+) 1185 WP_061348784.1 multidrug efflux MFS transporter EmrD -
  ACI3MI_RS03775 (ACI3MI_03775) yidF 467765..468262 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=959529 ACI3MI_RS03740 WP_000633668.1 462788..463378(-) (letA) [Escherichia coli strain 98223]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=959529 ACI3MI_RS03740 WP_000633668.1 462788..463378(-) (letA) [Escherichia coli strain 98223]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGTCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378