Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ACIQTD_RS11975 Genome accession   NZ_CP173185
Coordinates   2444824..2446815 (-) Length   663 a.a.
NCBI ID   WP_270250592.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain MGEL24009     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2439824..2451815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIQTD_RS11950 - 2440211..2441392 (-) 1182 WP_270250596.1 ABC transporter permease -
  ACIQTD_RS11955 - 2441459..2441743 (-) 285 WP_226898144.1 hypothetical protein -
  ACIQTD_RS11960 - 2441969..2442853 (-) 885 WP_012898698.1 XRE/MutR family transcriptional regulator -
  ACIQTD_RS11965 ruvB 2442990..2443991 (-) 1002 WP_404399200.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  ACIQTD_RS11970 ruvA 2444118..2444711 (-) 594 WP_270250595.1 Holliday junction branch migration protein RuvA Machinery gene
  ACIQTD_RS11975 hexB 2444824..2446815 (-) 1992 WP_270250592.1 DNA mismatch repair endonuclease MutL Machinery gene
  ACIQTD_RS11980 - 2446944..2447639 (-) 696 WP_023190211.1 hypothetical protein -
  ACIQTD_RS11985 hexA 2447754..2450276 (-) 2523 WP_270250590.1 DNA mismatch repair protein MutS Machinery gene
  ACIQTD_RS11990 - 2450469..2450816 (-) 348 WP_012898702.1 RicAFT regulatory complex protein RicA family protein -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 74596.88 Da        Isoelectric Point: 5.0738

>NTDB_id=957078 ACIQTD_RS11975 WP_270250592.1 2444824..2446815(-) (hexB) [Lactococcus lactis subsp. lactis strain MGEL24009]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTAEEESGTKLIAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFELTGYVSIP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFSILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKESLSVQTELPLQNNPLYYDNVRQDFYVREEATFKINKNQASNDSSEQTFDNFTE
NQLNTDAVSEKMTDRTVESTTEITDNSLEITDNSLENTVSNFEIDFDNEVKISQSSTFPQLEYLAQLHATYLLCQSKEGL
YLVDQHAAQERIKYEYWKDKIGEVSMEQQILLAPYLFTLPKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKE
TEIEKSINEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLAELATCKNPYSCAHGRPTIVHFSGDD
IQKMFRRIQETHRSKVASWKDFE

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=957078 ACIQTD_RS11975 WP_270250592.1 2444824..2446815(-) (hexB) [Lactococcus lactis subsp. lactis strain MGEL24009]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGAGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCTGGTTTGCGAT
TAATTGAAGTCATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTACGTCGTCATGCAACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTCGGTTTTCGGGGGGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGCTGAGGAAGAATCAGGAACAAAACTAATTGCTAAAGGTGGAAATATCGAAACTT
TAGAACCACTTGCTAAGCGCGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAATACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GCATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGTTCAGACTTAGATTTTGAACTAACAGGTTATGTCAGCATACCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGTCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGATATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTTCTATTTTATCGATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAAGCTTTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
GAGTCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATGTTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAAGCTTCAAATGATTCGTCTGAACAAACTTTTGATAATTTTACAGAA
AATCAACTTAATACAGATGCTGTCAGTGAAAAAATGACTGACAGAACTGTTGAAAGTACTACTGAAATTACTGACAACAG
TCTAGAAATTACTGACAACAGTCTAGAAAATACTGTCAGCAACTTTGAAATTGATTTTGATAATGAAGTAAAGATAAGTC
AGTCATCAACTTTTCCGCAGCTTGAATACTTGGCACAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTT
TATTTGGTTGACCAACATGCGGCTCAAGAGCGAATCAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGA
GCAACAAATTTTACTTGCACCATATTTGTTCACTTTACCCAAAAATGATTTTATTGTTTTAGCCGAGAAGAAAGATTTGT
TGCATGAAGCCGGTGTTTTCTTAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAA
ACCGAGATAGAGAAATCAATTAATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCAAAAAATATCGTCA
TGATTTAGCTGCAATGGTTGCTTGTAAAAGTTCAATTAAAGCTAATCATCCCCTTGATGCCGAATCAGCTAGAGCATTGC
TTGCAGAATTAGCAACTTGTAAAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGAC
ATTCAAAAAATGTTCCGGAGAATCCAAGAAACGCATCGTTCAAAAGTAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(462-605)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

56.383

99.246

0.56