Detailed information NTG0957039

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: ACIQTD_RS08975
• Genome accession: NZ_CP173185
• Coordinates: 1868491..1869858 (-)
• Length: 455 a.a.
• NCBI ID: WP_017864854.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain MGEL24009
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 1863491..1874858

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIQTD_RS08960	-	1864661..1866094 (-)	1434	WP_021722126.1	6-phospho-beta-glucosidase	-
ACIQTD_RS08965	yidD	1866218..1866484 (-)	267	WP_010906087.1	membrane protein insertion efficiency factor YidD	-
ACIQTD_RS08970	-	1866601..1868343 (-)	1743	WP_404399144.1	1-deoxy-D-xylulose-5-phosphate synthase	-
ACIQTD_RS08975	ciaH	1868491..1869858 (-)	1368	WP_017864854.1	cell wall metabolism sensor histidine kinase WalK	Regulator
ACIQTD_RS08980	ciaR	1869952..1870620 (-)	669	WP_021722129.1	response regulator transcription factor	Regulator
ACIQTD_RS08985	-	1870798..1871772 (-)	975	WP_003130365.1	LacI family DNA-binding transcriptional regulator	-
ACIQTD_RS08990	-	1871925..1874180 (-)	2256	WP_404399145.1	glycoside hydrolase family 65 protein	-

Sequence

Protein

• Length: 455 a.a.
• Molecular weight: 51200.75 Da
• Isoelectric Point: 9.4771

>NTDB_id=957039 ACIQTD_RS08975 WP_017864854.1 1868491..1869858(-) (ciaH) [Lactococcus lactis subsp. lactis strain MGEL24009]
MKKIIKKIKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLEEAANNQLGTSSSQD
SGFGPNNSVIFYDSEGKNFMPSTGSNANISTNFGMSLLQKAMKFNEKHINTIQTVSVKNPYGDNLHYRYYTTSQFIITNS
DGTVTPVYMQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSIIISLYLANWTLRPILAAYEKQKEFVENASHELRTPLAIL
QNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKFS
GHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKARTR
QKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide

• Length: 1368 bp

>NTDB_id=957039 ACIQTD_RS08975 WP_017864854.1 1868491..1869858(-) (ciaH) [Lactococcus lactis subsp. lactis strain MGEL24009]
TTGAAGAAAATAATTAAAAAAATTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTGTTTTTGGAAGAAGCAGCGAATAATCAATTAGGAACAAGTAGTTCACAAGAC
AGTGGCTTTGGACCTAATAATAGTGTAATTTTTTATGATTCAGAAGGAAAAAACTTTATGCCGTCAACGGGCTCAAATGC
AAATATAAGTACAAACTTTGGCATGAGTCTTTTGCAAAAAGCAATGAAATTTAATGAAAAACATATAAATACAATTCAGA
CAGTATCTGTAAAAAATCCTTATGGAGATAATTTGCACTATCGTTATTACACAACATCGCAATTTATCATTACAAATTCT
GATGGTACTGTGACGCCAGTTTATATGCAAATTTTTTCAAACGTTGACCAAATTCAAGATGCCATGAGTCGTGCCATGTG
GGTCATTGTGACAACAATGATTACTTTCTGGCTACTATCAATAATTATTAGTTTGTATCTTGCAAATTGGACATTAAGAC
CTATTCTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATCTTG
CAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTTATC
AGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGCCAG
AGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTTTCA
GGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATCAAACAATTGCTAACCATATTATTTGATAATGC
TCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGAGGATTCTTAGTTTTTGCTGTCGCCG
ATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACGCGT
CAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGAAGA
TAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCCAAA
AGTTGTAA

Domains

Predicted by InterProScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (222-288)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (332-441)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	48.372	94.505	0.457
ciaH	Streptococcus pneumoniae Rx1	44.444	98.901	0.44
ciaH	Streptococcus pneumoniae D39	44.444	98.901	0.44
ciaH	Streptococcus pneumoniae R6	44.444	98.901	0.44
ciaH	Streptococcus pneumoniae TIGR4	44.444	98.901	0.44