Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   AAA996_RS10060 Genome accession   NZ_AP028606
Coordinates   1943188..1943682 (-) Length   164 a.a.
NCBI ID   WP_224781507.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep1     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1938188..1948682
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA996_RS10030 (TKY121773_19380) - 1938497..1939372 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  AAA996_RS10035 (TKY121773_19390) pstC 1939490..1940353 (+) 864 WP_000165892.1 phosphate ABC transporter permease subunit PstC -
  AAA996_RS10040 (TKY121773_19400) pstA 1940346..1941161 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  AAA996_RS10045 (TKY121773_19410) pstB 1941163..1941915 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  AAA996_RS10050 (TKY121773_19420) phoU 1941930..1942580 (+) 651 WP_001245783.1 phosphate signaling complex protein PhoU -
  AAA996_RS10055 (TKY121773_19430) - 1942642..1943073 (+) 432 Protein_1940 transposase -
  AAA996_RS10060 (TKY121773_19440) comR 1943188..1943682 (-) 495 WP_224781507.1 helix-turn-helix transcriptional regulator Regulator
  AAA996_RS10065 (TKY121773_19450) - 1943840..1944856 (+) 1017 WP_000415107.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  AAA996_RS10070 (TKY121773_19460) galU 1944878..1945777 (+) 900 WP_000202226.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  AAA996_RS10075 (TKY121773_19470) - 1945844..1946521 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  AAA996_RS10080 (TKY121773_19480) - 1946505..1947044 (-) 540 WP_000834342.1 5-formyltetrahydrofolate cyclo-ligase -
  AAA996_RS10085 (TKY121773_19490) - 1947056..1948186 (-) 1131 WP_000885069.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 164 a.a.        Molecular weight: 19780.85 Da        Isoelectric Point: 4.8839

>NTDB_id=95655 AAA996_RS10060 WP_224781507.1 1943188..1943682(-) (comR) [Streptococcus pneumoniae strain Sep1]
MIQYMLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYK
LMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEI
LSFW

Nucleotide


Download         Length: 495 bp        

>NTDB_id=95655 AAA996_RS10060 WP_224781507.1 1943188..1943682(-) (comR) [Streptococcus pneumoniae strain Sep1]
TTGATTCAGTATATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAA
AAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTA
GAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAG
TTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGA
TGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAA
GATTTATCATCCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATA
CTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(90-137)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

73.171

0.409
  comR Streptococcus pyogenes MGAS315

54.167

73.171

0.396
  comR Streptococcus mutans UA159

52.5

73.171

0.384

Multiple sequence alignment