Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   QMM33_RS10375 Genome accession   NZ_AP025940
Coordinates   2044084..2045382 (-) Length   432 a.a.
NCBI ID   WP_050207064.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700204     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2039084..2050382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM33_RS10355 (PC0204_19920) rplI 2040238..2040690 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  QMM33_RS10360 (PC0204_19930) - 2040687..2042660 (-) 1974 WP_000715111.1 DHH family phosphoesterase -
  QMM33_RS10365 (PC0204_19940) raiA 2042797..2043345 (-) 549 WP_000599104.1 ribosome-associated translation inhibitor RaiA -
  QMM33_RS10370 (PC0204_19950) comFC/cflB 2043425..2044087 (-) 663 WP_281737396.1 ComF family protein Machinery gene
  QMM33_RS10375 (PC0204_19960) comFA/cflA 2044084..2045382 (-) 1299 WP_050207064.1 DEAD/DEAH box helicase Machinery gene
  QMM33_RS10380 (PC0204_19970) - 2045438..2046073 (+) 636 WP_000395739.1 YigZ family protein -
  QMM33_RS10385 (PC0204_19980) cysK 2046358..2047284 (+) 927 WP_000029873.1 cysteine synthase A -
  QMM33_RS10390 (PC0204_19990) tsf 2047405..2048445 (-) 1041 WP_000808063.1 translation elongation factor Ts -
  QMM33_RS10395 (PC0204_20000) rpsB 2048523..2049302 (-) 780 WP_000268466.1 30S ribosomal protein S2 -
  QMM33_RS10400 - 2049749..2050030 (+) 282 Protein_2016 transposase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49527.42 Da        Isoelectric Point: 8.2050

>NTDB_id=95556 QMM33_RS10375 WP_050207064.1 2044084..2045382(-) (comFA/cflA) [Streptococcus pneumoniae strain PZ900700204]
MKVNLDYLGCLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCNSTILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASSRIDVCLELYKR
LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTLYHAVKNSVKENGLRIFLTATST
NELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSDFNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEI
LQEQFPNEKIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=95556 QMM33_RS10375 WP_050207064.1 2044084..2045382(-) (comFA/cflA) [Streptococcus pneumoniae strain PZ900700204]
ATGAAAGTAAATTTAGATTATCTCGGTTGTTTATTTACTGAGAATGAATTAACAGAAGAAGAACGTCAGTTGGCGGAGAA
ACTTCCAGCAATGAGAAAGGAGAAGGGGAAACTTTTCTGTCAACGTTGTAATAGTACTATTCTAGAAGAATGGTATTTGC
CCATCGGTGCTTACTATTGTCGAGAGTGCTTGCTGATGAAGCGAGTCAGAAGTGATCAAACTTTATACTATTTTCCGCAG
GAGGATTTTCCGAAGCAAGATGTTCTCAAATGGCGCGGCCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGACTGCT
TCAAGCAGTAGACAAGCAAAAGCCAACCTTAGTTCATGCGGTAACAGGAGCTGGAAAGACAGAAATGATTTATCAAGTAG
TGGCTAAAGTGATCAATGCGGGTGGTGCAGTGTGTTTGGCTAGTTCTCGCATAGATGTTTGTTTGGAGCTGTACAAGCGC
CTGCAACAGGATTTTTCTTGCGGGATAGCTTTGCTACATGGAGAATCGGAACCTTATTTTCGAACACCACTAGTTGTTGC
AACAACCCATCAGTTATTGAAGTTTTATCAAGCTTTTGATTTGCTGATAGTGGATGAAGTAGATGCTTTTCCTTATGTTG
ATAATCCCACGCTTTACCATGCTGTCAAGAATAGTGTAAAGGAGAATGGATTGAGAATCTTTTTAACAGCGACTTCGACC
AATGAGTTAGATAAAAAGGTCCGTTTAGGAGAACTAAAAAGACTGAATTTACCGAGACGGTTTCATGGAAATCCGTTGAT
TATTCCAAAACCAATTTGGTTATCGGATTTTAATCGCTACTTAGACAAGAATCGTTTGTCACCAAAGTTAAAGTCCTATA
TTGAGAAGCAGAGAAAGACAGCTTATCCGTTACTCATTTTTGCTTCAGAAATTAAGAAAGGGGAGCAGTTAGAAGAAATC
TTACAGGAGCAATTTCCAAATGAGAAAATTGGCTTTGTATCTTCTGTAACAGAGGATCGATTAGAGCAAGTACAAGCTTT
TCGAGATGGAGAACTGACAATACTTATCAGTACGACAATCTTGGAGCGTGGAGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAGGCCAATCATCGTTTGTTTACCAAGTCTAGTTTGATTCAGATTGGTGGACGAGTTGGACGAAGCATGGATAGA
CCGACAGGAGATTTGCTTTTCTTCCATGATGGGTTAAATGCTTCAATCAAGAAGGCGATTAAGGAAATTCAGATGATGAA
TAAGGAGGCTGGTCTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(293-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

99.074

100

0.991
  comFA/cflA Streptococcus pneumoniae D39

99.074

100

0.991
  comFA/cflA Streptococcus pneumoniae R6

99.074

100

0.991
  comFA/cflA Streptococcus pneumoniae TIGR4

98.843

100

0.988
  comFA/cflA Streptococcus mitis NCTC 12261

92.824

100

0.928
  comFA/cflA Streptococcus mitis SK321

91.667

100

0.917
  comFA Lactococcus lactis subsp. cremoris KW2

51.716

94.444

0.488
  comFA Latilactobacillus sakei subsp. sakei 23K

39.563

95.37

0.377

Multiple sequence alignment