Detailed information NTG0095538

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: QMM33_RS09225
• Genome accession: NZ_AP025940
• Coordinates: 1821112..1822122 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900700204
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1816112..1827122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM33_RS09200 (PC0204_17940)	-	1817233..1817526 (-)	294	WP_000977367.1	hypothetical protein	-
QMM33_RS09205 (PC0204_17950)	-	1817688..1818140 (+)	453	WP_000079154.1	universal stress protein	-
QMM33_RS09210 (PC0204_17960)	-	1818175..1819563 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
QMM33_RS09215 (PC0204_17970)	-	1819629..1820591 (+)	963	WP_001124777.1	asparaginase	-
QMM33_RS09220 (PC0204_17980)	-	1820620..1821048 (-)	429	WP_138008642.1	hypothetical protein	-
QMM33_RS09225 (PC0204_17990)	ccpA	1821112..1822122 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
QMM33_RS09230 (PC0204_18000)	-	1822547..1823146 (-)	600	WP_000866703.1	response regulator transcription factor	-
QMM33_RS09235 (PC0204_18010)	-	1823147..1824244 (-)	1098	WP_050204938.1	sensor histidine kinase	-
QMM33_RS09240 (PC0204_18020)	-	1824244..1824981 (-)	738	WP_000832827.1	ABC transporter permease	-
QMM33_RS09245 (PC0204_18030)	-	1824983..1825867 (-)	885	WP_000219362.1	ABC transporter ATP-binding protein	-
QMM33_RS09250 (PC0204_18040)	-	1825854..1826048 (-)	195	WP_050204940.1	hypothetical protein	-
QMM33_RS09255	-	1826045..1826251 (-)	207	Protein_1816	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=95538 QMM33_RS09225 WP_000990607.1 1821112..1822122(-) (ccpA) [Streptococcus pneumoniae strain PZ900700204]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=95538 QMM33_RS09225 WP_000990607.1 1821112..1822122(-) (ccpA) [Streptococcus pneumoniae strain PZ900700204]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568