Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   QMM27_RS08645 Genome accession   NZ_AP025939
Coordinates   1704452..1705072 (-) Length   206 a.a.
NCBI ID   WP_084572333.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Utah_35B-24     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1693803..1716062 1704452..1705072 within 0


Gene organization within MGE regions


Location: 1693803..1716062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM27_RS08585 (Utah35B_16860) - 1693803..1694597 (-) 795 WP_001101210.1 hypothetical protein -
  QMM27_RS08590 (Utah35B_16870) - 1695005..1695430 (-) 426 WP_000204065.1 hypothetical protein -
  QMM27_RS08595 (Utah35B_16880) - 1695559..1695918 (-) 360 WP_000749822.1 hypothetical protein -
  QMM27_RS08600 (Utah35B_16890) - 1695964..1696170 (-) 207 WP_000366091.1 hypothetical protein -
  QMM27_RS08605 (Utah35B_16900) - 1696157..1696330 (-) 174 WP_000289349.1 helix-turn-helix transcriptional regulator -
  QMM27_RS08610 (Utah35B_16910) lytA 1696689..1697645 (-) 957 WP_000405235.1 N-acetylmuramoyl-L-alanine amidase LytA -
  QMM27_RS08615 (Utah35B_16920) - 1698021..1699391 (-) 1371 WP_001036271.1 MATE family efflux transporter -
  QMM27_RS08620 (Utah35B_16930) recA 1699698..1700864 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  QMM27_RS08625 (Utah35B_16940) cinA 1700919..1702175 (-) 1257 WP_000642706.1 competence/damage-inducible protein A Machinery gene
  QMM27_RS08630 (Utah35B_16950) - 1702260..1703276 (-) 1017 WP_000239282.1 LCP family protein -
  QMM27_RS08635 (Utah35B_16960) - 1703284..1703802 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  QMM27_RS08640 (Utah35B_16970) tsaE 1703792..1704235 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  QMM27_RS08645 (Utah35B_16980) comM 1704452..1705072 (-) 621 WP_084572333.1 hypothetical protein Regulator
  QMM27_RS08650 (Utah35B_16990) - 1705378..1706241 (-) 864 WP_001093641.1 helix-turn-helix transcriptional regulator -
  QMM27_RS08655 (Utah35B_17000) - 1706433..1706603 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  QMM27_RS08660 (Utah35B_17010) pneA1 1706706..1706930 (+) 225 WP_000181087.1 two-peptide bacteriocin subunit PneA1 -
  QMM27_RS08665 (Utah35B_17020) pneA2 1706937..1707125 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -
  QMM27_RS08670 (Utah35B_17030) lanM 1707240..1710230 (+) 2991 WP_000875573.1 type 2 lanthipeptide synthetase LanM -
  QMM27_RS08675 (Utah35B_17040) - 1710580..1711284 (+) 705 WP_001033170.1 flavodoxin family protein -
  QMM27_RS08680 (Utah35B_17050) - 1711265..1712194 (+) 930 WP_000912954.1 M50 family metallopeptidase -
  QMM27_RS08685 (Utah35B_17060) - 1712191..1714299 (+) 2109 WP_000701298.1 peptidase domain-containing ABC transporter -
  QMM27_RS08690 (Utah35B_17070) - 1714323..1716062 (+) 1740 WP_000699969.1 S8 family serine peptidase -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23485.63 Da        Isoelectric Point: 10.0081

>NTDB_id=95457 QMM27_RS08645 WP_084572333.1 1704452..1705072(-) (comM) [Streptococcus pneumoniae strain Utah_35B-24]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYIHDLLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIATLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=95457 QMM27_RS08645 WP_084572333.1 1704452..1705072(-) (comM) [Streptococcus pneumoniae strain Utah_35B-24]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAAGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGTATGGTCTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCAGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTATTAGGAGCTGTCCTTGTCTTGTCAGATAACTTGTTCATTAAAAATACGTTGCAGCAAGAATTAGTTGACTT
TTTGTTGCCATCCTTTTTCTTTCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACATACACGATTTGC
TTGCTATGCTAGATAGAAAAAAGACGGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTCTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGCTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

98.058

100

0.981
  comM Streptococcus pneumoniae R6

98.058

100

0.981
  comM Streptococcus pneumoniae TIGR4

98.058

100

0.981
  comM Streptococcus mitis SK321

38.974

94.66

0.369
  comM Streptococcus mitis NCTC 12261

38.462

94.66

0.364

Multiple sequence alignment