Detailed information NTG0095408

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AAA980_RS10070
• Genome accession: NZ_AP028604
• Coordinates: 1921021..1921920 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904870.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Pne3
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1916021..1926920

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA980_RS10045 (TKY182805_19750)	rsmA	1916351..1917223 (-)	873	WP_001216877.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
AAA980_RS10050 (TKY182805_19760)	-	1917354..1917662 (-)	309	WP_000333257.1	hypothetical protein	-
AAA980_RS10055 (TKY182805_19770)	-	1917655..1918296 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
AAA980_RS10060 (TKY182805_19780)	-	1918298..1920328 (-)	2031	WP_000825278.1	bacteriocin-associated integral membrane family protein	-
AAA980_RS10065 (TKY182805_19790)	-	1920405..1920701 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
AAA980_RS10070 (TKY182805_19800)	comR	1921021..1921920 (-)	900	WP_000904870.1	helix-turn-helix transcriptional regulator	Regulator
AAA980_RS10075 (TKY182805_19810)	rnmV	1921992..1922552 (-)	561	WP_000660015.1	ribonuclease M5	-
AAA980_RS10080 (TKY182805_19820)	-	1922552..1923325 (-)	774	WP_000575621.1	TatD family hydrolase	-
AAA980_RS10085 (TKY182805_19830)	-	1923621..1924319 (-)	699	WP_232036507.1	DUF1542 domain-containing protein	-
AAA980_RS10090 (TKY182805_19840)	rpmH	1924558..1924692 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
AAA980_RS10095 (TKY182805_19850)	-	1924837..1926051 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
AAA980_RS10100	-	1926207..1926500 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35351.12 Da
• Isoelectric Point: 4.8336

>NTDB_id=95408 AAA980_RS10070 WP_000904870.1 1921021..1921920(-) (comR) [Streptococcus pneumoniae strain Pne3]
MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=95408 AAA980_RS10070 WP_000904870.1 1921021..1921920(-) (comR) [Streptococcus pneumoniae strain Pne3]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAGTTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361